N-phenylacetyl-N'-p-tolyl-urea | 34265-83-3

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: N-phenylacetyl-N'-p-tolyl-urea
• 英文别名: N-p-Tolyl-N'-phenacetyl-harnstoff；N-Phenylacetyl-N'-p-tolyl-harnstoff
• CAS: 34265-83-3
• 化学式: C₁₆H₁₆N₂O₂
• 分子量: 268.315
• InChiKey: KTOLATARWDDQTN-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.89
• 重原子数：
  20.0
• 可旋转键数：
  3.0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.12
• 拓扑面积：
  58.2
• 氢给体数：
  2.0
• 氢受体数：
  2.0

反应信息

• 作为产物：
  描述：

  N-phenylacetyl-N'-p-tolyl-thiourea 在 silver nitrate 作用下， 生成 N-phenylacetyl-N'-p-tolyl-urea
  参考文献：
  名称：

  Ten Ways to Reduce Detention Population

  摘要：

  ABSTRACT“Juvenile detention is regularly overlooked, maligned, and misunderstood. Its embattled condition is best described as severely abused and neglected. It is underfunded, understaffed, crowded and largely ignored.”1“Detention caseloads increased 38 percent between 1987 and 1996. The increase in the number of delinquency cases handled by the courts has driven the growth in the number of juveniles in the detention system. In 1987, 1.2 million delinquency cases were disposed of in juvenile courts. By 1996, this number had risen 49 percent, to almost 1.8 million. This increase in the volume of juveniles in the justice system resulted in a 38 percent increase in the number of delinquency cases that involved the use of detention. The number of juvenile delinquency cases detained in 1996 was 89,000 more than in 1987. This has resulted in increased demand for juvenile detention bed space across the country.”2“Changes in statutes allowing more detainable offenses have significantly increased the number of youths admitted to regional detention centers.”3“Although minority youth constituted about 32 percent of the youth population in the country in 1995, they represented 68 percent of the juvenile population in secure detention…4

  DOI：

  10.1111/j.1755-6988.2001.tb00036.x

文献信息

• The Reactions of Complexes of Thioboronite with Compounds Containing Carbon-Nitrogen Multiple Bond
  作者：Teruaki Mukaiyama、Shoji Yamamoto、Katsuhiko Inomata

  DOI：10.1246/bcsj.44.2807

  日期：1971.10

  n-Butyl di-n-butylthioboronite reacts with isocyanates to give 1:2 adducts, and with isothiocyanate or carbodiimide to give a 1:1 adduct. It was found that thioboronite forms a 1:1 co-ordinated complex with benzyl cyanide, and that the complex reacts with isocyanates to give the corresponding acetamidine derivatives in good yields.

  正丁基二正丁基硫代硼酸盐与异氰酸酯反应生成 1:2 的加合物，与异硫氰酸酯或碳二亚胺反应生成 1:1 的加合物。发现硫代硼酸盐与苄基氰化物形成 1:1 配位络合物，并且该络合物与异氰酸酯反应以良好的产率得到相应的乙脒衍生物。