tert.butyl-peroxyacetate | 99116-05-9

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: tert.butyl-peroxyacetate
• 英文别名: 3,3-Dimethylbutaneperoxoic acid
• CAS: 99116-05-9
• 化学式: C₆H₁₂O₃
• 分子量: 132.159
• InChiKey: RQLGMECUXRQENU-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.3
• 重原子数：
  9
• 可旋转键数：
  3
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.83
• 拓扑面积：
  46.5
• 氢给体数：
  1
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  tert.butyl-peroxyacetate 、 [FeIII(TMP)(OH)] 以 二氯甲烷 为溶剂， 生成
  参考文献：
  名称：

  Acylperoxo-Iron(III) Porphyrin Complexes: A New Entry of Potent Oxidants for the Alkene Epoxidation

  摘要：

  Competitive epoxidation of norbornylene and alpha-methylstyrene by peracids in the presence of iron porphyrins has been carried out in methylene chloride and toluene at -78 degrees C. When (TMP)Fe-III(RCO(2)) (TMP = 5,10,15,20-tetramesitylporphyrin) is used as a catalyst in methylene chloride, selectivity of norbornylene oxide over alpha-methylstyrene oxide is almost identical even though a variety of peracids are used, since O=Fe(IV)TMP pi-cation radical 2a is the common oxidant in the reactions. On the other hand, the selectivity in the epoxidations catalyzed by (TDCPP)Fe-III(X) (TDCPP: 5,10,15,20-tetrakis(2,6-dichlorophenyl)porphyrin is found to be dependent on the structure of peracids. The latter type of the results is also obtained for the reactions catalyzed both by (TMP)Fe-III(X) and by (TDCPP)Fe-III(X) in toluene. The dependence of the selectivity in the epoxidation on the structure of peracids is attributed to the alteration of the oxidant from 2 to peracid-Fe(III) complexes 1. The direct involvement of 1 in the epoxidation has been further confirmed by spectroscopic studies of the reactions. Under the catalytic epoxidation conditions at low temperature, the participation of 1 and 2 as the active species is controlled either by electronic structure of iron porphyrin complexes (push-pull effect) or by alteration of the solvent.

  DOI：

  10.1021/ja00130a007
• 作为试剂：
  描述：

  苯磺酰胺 、 乙基苯 在 1,10-菲罗啉 tert.butyl-peroxyacetate 、 4 A molecular sieve 、 copper(II) bis(trifluoromethanesulfonate) 作用下， 以 1,2-二氯乙烷 为溶剂， 反应 6.0h， 以60%的产率得到N-(1-苯基乙基)苯磺酰胺
  参考文献：
  名称：

  铜催化的烯丙基和苄基CH键的酰胺化。

  摘要：

  [结构：见正文]描述了铜催化的烯丙基和苄基CH键与伯磺酰胺和仲磺酰胺的酰胺化。该反应适用于各种烃类与芳基，杂芳基和烷基磺酰胺的偶联，并且耐受多种官能团。通过分离乙酸苄酯中间体已经获得了机理上的见识，该中间体被证明在铜催化下易于转化为取代的磺酰胺产物。

  DOI：

  10.1021/ol062514u

文献信息

• SILANE COUPLING COMPOUNDS AND MEDICAL AND/OR DENTAL CURABLE COMPOSITIONS COMPRISING THE SAME
  申请人：KABUSHIKI KAISHA SHOFU

  公开号：US20190300552A1

  公开（公告）日：2019-10-03

  The present invention relate to a novel silane coupling agent and a medical and/or dental curable composition comprising the same. It is an object of the present invention to provide a novel silane coupling agent that imparts high affinity to a radical polymerizable monomer, thereby imparting high mechanical strength, flexibility and durability when used for a medical and/or dental curable composition, and an inorganic filler surface-treated with the novel silane coupling agent and a novel medical and/or dental curable composition. A silane coupling agent including repeating units such as a urethane bond and polyethylene glycol (ether bond) at a specific position is used.

  本发明涉及一种新型硅烷偶联剂以及包括该偶联剂的医用和/或牙科可固化组合物。本发明的目的是提供一种新型硅烷偶联剂，使其对自由基聚合单体具有高亲和力，从而在用于医用和/或牙科可固化组合物时赋予高机械强度、柔韧性和耐久性，并且包括经新型硅烷偶联剂表面处理的无机填料和新型医用和/或牙科可固化组合物。该硅烷偶联剂包括在特定位置具有尿素键和聚乙二醇（醚键）等重复单元。
• METHOD FOR MANUFACTURING FLUOROPOLYMERS
  申请人：SOLVAY SOLEXIS S.p.A.

  公开号：US20140228531A1

  公开（公告）日：2014-08-14

  The invention pertains to a method for making a fluoropolymer comprising an aqueous emulsion polymerization of one or more fluorinated monomers wherein said aqueous emulsion polymerization is carried out in the presence of at least one cyclic fluorocompound of the following formula (I): wherein X 1 , X 2 , X 3 , equal or different from each other are independently selected among H, F, and C 1-6 (per)fluoroalkyl groups, optionally comprising one or more catenary or non-catenary oxygen atoms; L represents a bond or a divalent group; R F is a divalent fluorinated C 1-3 bridging group; Y is a hydrophilic function selected among anionic functionalities, cationic functionalities and non-ionic functionalities.

  该发明涉及一种制备氟聚合物的方法，包括一种水乳液聚合的方法，其中所述水乳液聚合是在至少一种具有以下式(I)的环状氟化合物存在下进行的：其中X1、X2、X3相互独立且可相同或不同地选择自H、F和C1-6(per)氟烷基团，可选地包括一个或多个环链或非环链氧原子；L代表键或二价基团；RF是二价氟化的C1-3桥联基团；Y是在阴离子功能团、阳离子功能团和非离子功能团中选择的亲水功能。
• Expedient synthesis of oseltamivir and related compounds via direct olefin diazidation-diamidation reaction
  申请人：GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION, INC.

  公开号：US10385010B1

  公开（公告）日：2019-08-20

  Disclosed herein are improved methods for the preparation of oseltamivir, and intermediates useful thereto.

  本文披露了改进的奥司他韦制备方法，以及与之有关的有用中间体。
• Novel proton type beta zeolite, preparation method thereof and process for preparing phenol compound using the same
  申请人：UBE INDUSTRIES, LTD.

  公开号：US20040242938A1

  公开（公告）日：2004-12-02

  Disclosed are a proton type &bgr; zeolite in which an acid site showing a desorption peak with a range of ±100° C. with a center of 330° C. exists in a spectrum measured by the ammonia temperature programmed desorption method (NH 3 -TPD), and an amount of a strong acid site showing a desorption peak of 500° C. or higher is controlled to 2.5 &mgr;mol/g or less, a method for preparing the same, and a process for preparing a phenol compound by oxidizing a benzene compound with a peroxide in the presence of the proton type &bgr; zeolite.

  揭示了一种质子型β沸石，其中通过氨温度程序脱附法（NH3-TPD）测量的光谱中存在一个酸位显示出一个±100°C范围内的脱附峰，中心温度为330°C，并且控制强酸位显示出500°C或更高脱附峰的量为2.5μmol/g或更低，以及制备该沸石的方法和在质子型β沸石存在的情况下，在过氧化物存在下氧化苯化合物制备苯酚化合物的方法。
• Cell-Laden Hydrogels
  申请人：Khademhosseini Alireza

  公开号：US20080193536A1

  公开（公告）日：2008-08-14

  The present invention provides cell-laden hydrogels and hydrogel assemblies thereof for use in tissue engineering. The invention provides microscale hydrogels (i.e. microgels) having greatest dimensions ranging between about 1 μm and 1000 μm. The present invention provides methods of producing inventive hydrogels and hydrogel assemblies and pharmaceutical compositions thereof.

  本发明提供了含有细胞的水凝胶及其水凝胶组件，用于组织工程。该发明提供微观水凝胶（即微胶）的最大尺寸范围在约1μm至1000μm之间。本发明提供了生产创新水凝胶和水凝胶组件的方法，以及其制药组合物。