N,N-diethyl-2-methylidene-3-oxobutanamide | 20954-06-7

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: N,N-diethyl-2-methylidene-3-oxobutanamide
• 英文别名: α-Methylen-acetessigsaeure-diethylamid oder β-Hydroxycrotonsaeure-diethylamid；N,N-Diethyl-α-methylenacetoacetamid；2-Methylen-acetessigsaeure-diethylamid
• CAS: 20954-06-7
• 化学式: C₉H₁₅NO₂
• 分子量: 169.224
• InChiKey: YTZGWTOHQDTPKA-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.9
• 重原子数：
  12
• 可旋转键数：
  4
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.56
• 拓扑面积：
  37.4
• 氢给体数：
  0
• 氢受体数：
  2

文献信息

• CATALYTIC CYCLE FOR PRODUCTION OF 1,1-DISUBSTITUTED ALKENES
  申请人：Sirrus, Inc.

  公开号：US20200223779A1

  公开（公告）日：2020-07-16

  The present teachings disclose contacting an amine salt catalyst with a dicarbonyl compound having an alkylene group between the carbonyl group; adding formaldehyde, paraformaldehyde, or formalin in an amount of about 2:1 to about 3:1 moles of formaldehyde to moles of the dicarbonyl compound to form a mixture; and refluxing the mixture. The process forms a carbonyl-substituted alkene. The process may be performed in the absence of a solvent. The process may form methylene malonates, methylene dimalonates, methylene keto malonamides, methylene diketones, methylene keto esters, and the like.