diethyl [1-cyano-2-(2-thienyl)propanylid-3-ene]triphenylphosphorane-1,3-dicarboxylate | 530099-72-0

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: diethyl [1-cyano-2-(2-thienyl)propanylid-3-ene]triphenylphosphorane-1,3-dicarboxylate
• CAS: 530099-72-0
• 化学式: C₃₂H₃₀NO₄PS
• 分子量: 555.634
• InChiKey: SJEAQLCUXQEIPC-UHFFFAOYSA-N

反应信息

• 作为反应物：
  描述：

  对硝基苯甲醛 、 diethyl [1-cyano-2-(2-thienyl)propanylid-3-ene]triphenylphosphorane-1,3-dicarboxylate 以 乙酸乙酯 为溶剂， 反应 48.0h， 以45%的产率得到2-Cyano-4-[1-(4-nitro-phenyl)-meth-(Z)-ylidene]-3-thiophen-2-yl-pentanedioic acid diethyl ester
  参考文献：
  名称：

  The Reactions of Triphenylphosphine Alkylenes with 3(2-Thienyl)acrylonitriles

  摘要：

  Ethyl 3-(2-thienyl)acrylocyanoacetate (1b) reacts with ester ylide phosphoranes 2a,b in toluene, containing triethylamine, affording the Michael addition products 7a,b and the cyclopropanes 6a,b and 8a,b. The reaction of 1b with keto ylide 2c in ethyl acetate containing benzoic acid in addition to the ylide 76 the pyran 12 was obtained On the other hand, (cyanomethyl)triphenylphosphonium chloride (13) reacts, under the phase-transfer catalysis conditions, with 1b to give the cyclopropane derivative 15 whereas with la, the new ylide 16 along with the propene derivative 17 were obtained.

  DOI：

  10.1080/10426500307778
• 作为产物：
  描述：

  乙氧甲酰基亚甲基三苯基膦 、 乙基 2-氰基-3-(2-噻嗯基)丙烯酰酸 在 三乙胺 作用下， 以 甲苯 为溶剂， 反应 72.0h， 以29%的产率得到diethyl 1-cyano-2-(2-thienyl)cyclopropane-1,3-dicarboxylate
  参考文献：
  名称：

  The Reactions of Triphenylphosphine Alkylenes with 3(2-Thienyl)acrylonitriles

  摘要：

  Ethyl 3-(2-thienyl)acrylocyanoacetate (1b) reacts with ester ylide phosphoranes 2a,b in toluene, containing triethylamine, affording the Michael addition products 7a,b and the cyclopropanes 6a,b and 8a,b. The reaction of 1b with keto ylide 2c in ethyl acetate containing benzoic acid in addition to the ylide 76 the pyran 12 was obtained On the other hand, (cyanomethyl)triphenylphosphonium chloride (13) reacts, under the phase-transfer catalysis conditions, with 1b to give the cyclopropane derivative 15 whereas with la, the new ylide 16 along with the propene derivative 17 were obtained.

  DOI：

  10.1080/10426500307778