ethyl 5-((2,5-dibenzyloxy)phenyl)valerate | 128760-83-8

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯酚醚
• 英文名称: ethyl 5-((2,5-dibenzyloxy)phenyl)valerate
• 英文别名: Ethyl 5-[2,5-bis(phenylmethoxy)phenyl]pentanoate
• CAS: 128760-83-8
• 化学式: C₂₇H₃₀O₄
• 分子量: 418.533
• InChiKey: FTOGPDYVXSPPSI-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  6.2
• 重原子数：
  31
• 可旋转键数：
  13
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.3
• 拓扑面积：
  44.8
• 氢给体数：
  0
• 氢受体数：
  4

文献信息

• Quinoline derivatives as antagonists of leukotriene D4, compositions containing the same and processes for their preparation
  申请人：RHONE-POULENC RORER INTERNATIONAL (HOLDINGS) INC.

  公开号：EP0348155A1

  公开（公告）日：1989-12-27

  This invention relates to quinolinyl compounds of the general formula: and the use of these compounds as pharmacological agents which are lipoxygenase inhibitors and/or leukotriene antagonists possessing anti-inflammatory and anti-allergic properties and their pharmaceutical compositions and processes for this preparation.

  本发明涉及通式如下的喹啉基化合物： 以及将这些化合物用作具有抗炎和抗过敏特性的脂氧合酶抑制剂和/或白三烯拮抗剂的药剂及其药物组合物和制备工艺。
• Quinoline derivatives as antagonists of leukotriene d4, compositions containing the same and processes for their preparation
  申请人：Aventis Holdings Inc.

  公开号：EP0784052B1

  公开（公告）日：2004-09-01
• US4920131A
  申请人：——

  公开号：US4920131A

  公开（公告）日：1990-04-24
• [EN] QUINOLINE DERIVATIVES AS ANTAGONISTS OF LEUKOTRIENE D4
  申请人：RORER INTERNATIONAL (OVERSEAS) INC.

  公开号：WO1989012628A1

  公开（公告）日：1989-12-28

  (EN) This invention relates to quinolinyl compounds of general formula (I), and the use of these compounds as pharmacological agents which are lipoxygenase inhibitors and/or leukotriene antagonists possessing anti-inflammatory and anti-allergic properties and their pharmaceutical compositions and processes for this preparation.(FR) Cette invention concerne des composés de quinolinyle de la formule générale (I), ainsi que l'emploi de ces composés en tant qu'agents pharmacologiques inhibiteurs de lipoxygénase et/ou antagonistes de leukotriène possédant des propriétés anti-inflammatoires et anti-allergiques. Elle concerne également leurs compositions pharmaceutiques et des procédés de préparation.