methyl N-[(2S)-1-[(2S)-2-[5-[5-[2-[(2S)-1-[(2S)-2-(methoxycarbonylamino)-3-methylbutanoyl]pyrrolidin-2-yl]-3H-benzo[e]benzimidazol-7-yl]-4-methylthiophen-2-yl]-1H-imidazol-2-yl]pyrrolidin-1-yl]-3-methyl-1-oxobutan-2-yl]carbamate | 1315624-40-8

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: methyl N-[(2S)-1-[(2S)-2-[5-[5-[2-[(2S)-1-[(2S)-2-(methoxycarbonylamino)-3-methylbutanoyl]pyrrolidin-2-yl]-3H-benzo[e]benzimidazol-7-yl]-4-methylthiophen-2-yl]-1H-imidazol-2-yl]pyrrolidin-1-yl]-3-methyl-1-oxobutan-2-yl]carbamate
• CAS: 1315624-40-8
• 化学式: C₄₁H₅₀N₈O₆S
• 分子量: 782.964
• InChiKey: YUBCKUWLNGFEJJ-ULDMLYOQSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  6.2
• 重原子数：
  56
• 可旋转键数：
  12
• 环数：
  7.0
• sp3杂化的碳原子比例：
  0.46
• 拓扑面积：
  203
• 氢给体数：
  4
• 氢受体数：
  9

文献信息

• FUSED TRICYCLIC COMPOUNDS AND METHODS OF USE THEREOF FOR THE TREATMENT OF VIRAL DISEAS
  申请人：Chen Kevin X.

  公开号：US20130156731A1

  公开（公告）日：2013-06-20

  The present invention relates to novel Fused Tricyclic Compounds, compositions comprising at least one Fused Tricyclic Compound, and methods of using Fused Tricyclic Compounds for treating or preventing a viral infection or a virus-related disorder in a patient.
• FUSED TRICYCLIC COMPOUNDS AND METHODS OF USE THEREOF FOR THE TREATMENT OF VIRAL DISEASES
  申请人：Merck Sharp & Dohme Corp.

  公开号：US20170008879A1

  公开（公告）日：2017-01-12

  The present invention relates to novel Fused Tricyclic Compounds, compositions comprising at least one Fused Tricyclic Compound, and methods of using Fused Tricyclic Compounds for treating or preventing a viral infection or a virus-related disorder in a patient.
• US9796705B2
  申请人：——

  公开号：US9796705B2

  公开（公告）日：2017-10-24