Taurolidine citrate | 1333382-80-1

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: Taurolidine citrate
• 英文别名: 4-[(1,1-dioxo-1,2,4-thiadiazinan-4-yl)methyl]-1,2,4-thiadiazinane 1,1-dioxide;2-hydroxypropane-1,2,3-tricarboxylic acid
• CAS: 1333382-80-1
• 化学式: C13H24N4O11S2
• 分子量: 476.5
• InChiKey: RMTOBKFGSODIEJ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -3.92
• 重原子数：
  30
• 可旋转键数：
  7
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.77
• 拓扑面积：
  248
• 氢给体数：
  6
• 氢受体数：
  15

文献信息

• ANTI-COAGULANT INFUSION FLUID SOURCE
  申请人：Edwards Lifesciences Corporation

  公开号：EP2542156A2

  公开（公告）日：2013-01-09
• FORMULATIONS OF BRINCIDOFOVIR
  申请人：Chimerix, Inc.

  公开号：EP3474822A1

  公开（公告）日：2019-05-01
• CATHETER FLUID LOCK METHOD AND DEVICE
  申请人：APPLING M. WILLIAM

  公开号：US20070100298A1

  公开（公告）日：2007-05-03

  A technique for providing a fluid lock in an indwelling catheter, such as is used in hemo-dialysis; the catheter having an annular lumen surrounding a central lumen. The annular lumen, whether used for infusion or aspiration, has a set of ports which are aligned with each other along a circular circumference so that they intersect a common plane. That common plane is substantially perpendicular to the axis of the annular lumen. The catheter is implanted into a patient's cardio-vascular system. There are substantial down times between the blood cleaning procedures for which the catheter is implanted. Fluid is injected into the annular lumen which displaces any blood in the annular lumen proximal of the set of ports. This fluid is maintained in the annular lumen displacing blood throughout the down time of the catheter thereby providing fluid lock and avoiding blood clot within the annular lumen proximal of the set of ports. The ports in the annular lumen face radially outward to assure that the port edges do not snag on tissue when the catheter is inserted.
• IDENTIFICATION AND TARGETED MODULATION OF GENE SIGNALING NETWORKS
  申请人：CAMP4 THERAPEUTICS CORPORATION

  公开号：US20210254056A1

  公开（公告）日：2021-08-19

  The present invention provides methods and compositions for the evaluation, alteration and/or optimization of gene signaling. Methods and systems are also provided which exploit the information generated in the identification of new targets and non-canonical signaling pathways.
• US7833215B2
  申请人：——

  公开号：US7833215B2

  公开（公告）日：2010-11-16