2,4-bis-methoxycarbonyloxy-6-methyl-benzoic acid | 860752-66-5

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 2,4-bis-methoxycarbonyloxy-6-methyl-benzoic acid
• 英文别名: 2,4-Bis-methoxycarbonyloxy-6-methyl-benzoesaeure；4.6-Bis-(carbomethoxy-oxy)-2-methyl-benzoesaeure；Dicarbomethoxy-orsellinsaeure；2,4-Bis(methoxycarbonyloxy)-6-methylbenzoic acid
• CAS: 860752-66-5
• 化学式: C₁₂H₁₂O₈
• 分子量: 284.222
• InChiKey: VGGVHIYCBQMFPM-UHFFFAOYSA-N

物化性质

• 沸点：
  447.5±45.0 °C(Predicted)
• 密度：
  1.378±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  2.1
• 重原子数：
  20
• 可旋转键数：
  7
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.25
• 拓扑面积：
  108
• 氢给体数：
  1
• 氢受体数：
  8

反应信息

• 作为反应物：
  描述：

  2,4-bis-methoxycarbonyloxy-6-methyl-benzoic acid 在 sodium hydroxide 、 氯仿 、 五氯化磷 、 丙酮 作用下， 生成 红粉苔酸
  参考文献：
  名称：

  Patients’ views on out-of-hours care in general practice in Dublin

  摘要：

  Background Little is known regarding patients' views and levels of satisfaction with out-of-hours care in Irish general practice despite significant recent changes in service delivery.Aims This study aimed to record patients' experience of out-of-hours care on a specific occasion and elicit their satisfaction with out-of-hours care in general.Methods Patients requesting out-of-hours care in three south inner city Dublin practices in June and July 2000 were identified and sent an anonymous postal questionnaire.Results Two hundred and forty patients were identified and 58% responded to the questionnaire, The approximate call rate was 195 calls per 1,000 patients per year. Sixty-one per cent of patients used the co-operative service, 28% received a house call and 3% received telephone advice only; 86% are currently satisfied with out-of-hours care.Conclusions The majority of patients are satisfied with the current out-of-hours service. Telephone consultation rates are significantly lower than other countries. These findings need to be considered before the widespread introduction of systems involving increased telephone consultations.

  DOI：

  10.1007/bf03173889
• 作为产物：
  描述：

  alkaline earth salt of/the/ methylsulfuric acid 在 potassium permanganate 、 丙酮 作用下， 生成 2,4-bis-methoxycarbonyloxy-6-methyl-benzoic acid
  参考文献：
  名称：

  Hoesch, Chemische Berichte, 1913, vol. 46, p. 887

  摘要：

  DOI：

文献信息

• Fischer,E.; Hoesch, Justus Liebigs Annalen der Chemie, 1912, vol. 391, p. 368,369
  作者：Fischer,E.、Hoesch

  DOI：——

  日期：——
• 182. Lichen acids. Part II. The constitution of evernic acid and the synthesis of methyl evernate
  作者：Alexander Robertson、Richard John Stephenson

  DOI：10.1039/jr9320001388

  日期：——