[4-[[2-[(3-Amino-3-oxopropyl)carbamoyl]phenyl]sulfanylmethyl]phenyl] 2,2-dimethylpropanoate | 1352347-84-2

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: [4-[[2-[(3-Amino-3-oxopropyl)carbamoyl]phenyl]sulfanylmethyl]phenyl] 2,2-dimethylpropanoate
• CAS: 1352347-84-2
• 化学式: C₂₂H₂₆N₂O₄S
• 分子量: 414.525
• InChiKey: OWSSUYXDCHIQIL-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.2
• 重原子数：
  29
• 可旋转键数：
  10
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.32
• 拓扑面积：
  124
• 氢给体数：
  2
• 氢受体数：
  5

文献信息

• THIOETHER PRODRUG COMPOSITIONS AS ANTI-HIV AND ANTI-RETROVIRAL AGENTS
  申请人：Appella Daniel

  公开号：US20130096092A1

  公开（公告）日：2013-04-18

  Disclosed are inhibitors of retroviral growth of formula (I), that are useful in treatment of retroviral infections such as HIV. Also disclosed are a composition comprising a pharmaceutically acceptable carrier and at least one compound or salt of the invention, a method for inactivating a virus, a method for dissociating a metal ion from a zinc finger-containing protein, and a method for inhibiting the transmission of a virus.
• [EN] THIOETHER PRODRUG COMPOSITIONS AS ANTI-HIV AND ANTI-RETROVIRAL AGENTS<br/>[FR] COMPOSITIONS DE PRÉCURSEUR DE THIOÉTHER EN TANT QU'AGENTS ANTI-VIH ET ANTI-RÉTROVIRAUX
  申请人：US HEALTH

  公开号：WO2011156674A2

  公开（公告）日：2011-12-15

  Disclosed are inhibitors of retroviral growth of formula (I), that are useful in treatment of retroviral infections such as HIV. Also disclosed are a composition comprising a pharmaceutically acceptable carrier and at least one compound or salt of the invention, a method for inactivating a virus, a method for dissociating a metal ion from a zinc finger-containing protein, and a method for inhibiting the transmission of a virus.