2-methoxyethyl benzylcarbamate | 65935-29-7

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 2-methoxyethyl benzylcarbamate
• 英文别名: 2-methoxyethyl N-benzylcarbamate
• CAS: 65935-29-7
• 化学式: C₁₁H₁₅NO₃
• 分子量: 209.245
• InChiKey: YKUBARNRUZRWNY-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.3
• 重原子数：
  15
• 可旋转键数：
  6
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.36
• 拓扑面积：
  47.6
• 氢给体数：
  1
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  2-methoxyethyl benzylcarbamate 在 potassium phosphate 、 1,10-菲罗啉 、 copper(ll) sulfate pentahydrate 、 三氟甲磺酸三甲基硅酯 作用下， 以 二氯甲烷 、 甲苯 为溶剂， 反应 26.0h， 生成 2-methoxyethylbenzyl(4-(4-hydroxybutyl)-2-oxo-5-phenyl3,4-dihydro-2H-1,3-oxazin-6-yl)carbamate
  参考文献：
  名称：

  Synthesis of a 3,4-Dihydro-1,3-oxazin-2-ones Skeleton via an Intermolecular [4 + 2] Process of N-Acyliminium Ions with Ynamides/Terminal Alkynes

  摘要：

  An approach to access functionalized 3,4-dihydro-1,3-oxazin-2-ones has been developed by reacting semicyclic N,O-acetals 5 and 6 with ynamides 7 or terminal alkynes 8 in a one-pot fashion. The reaction went through a formal [4 + 2] cycloaddition process to generate a number of functionalized 3,4-dihydro-1,3-oxazin-2-ones 9a-9ak and 10a-10bc in yields of 34-97%. In addition, the utility of this transformation was demonstrated by the synthesis of (±)-sedamine 13.

  DOI：

  10.1021/acs.joc.0c01692
• 作为产物：
  描述：

  3-methyl-1-(2-methoxyethyloxy)carbonyl-1H-imidazol-3-ium iodide 、 苄胺 在 三乙胺 作用下， 以 乙腈 为溶剂， 反应 24.0h， 以70%的产率得到2-methoxyethyl benzylcarbamate
  参考文献：
  名称：

  Method for the synthesis of N-alkyl-O-alkyl carbamates

  摘要：

  合成N-烷基，O-烷基氨基甲酸酯的简单三步方法。

  DOI：

  10.1039/c4ra00373j

文献信息

• CELLULOSE ACYLATE FILM, POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY DEVICE
  申请人：FUJIFILM Corporation

  公开号：US20160060406A1

  公开（公告）日：2016-03-03

  The cellulose acylate film includes a compound denoted by formula 1 below: wherein, in formula 1, Het denotes an optionally substituted aromatic hetero ring; X 1 denotes a single bond or a group selected from the group consisting of —O—, —NR 2 —, —CR 3 R 4 —, —S—, and —CO—; each of R 2 , R 3 , and R 4 independently denotes a hydrogen atom or a substituent; R 1 denotes a partial structure of valence n, with n denoting an integer greater than or equal to 1; wherein the compound includes at least one group selected from the group consisting of —NH— and —CO— per molecule, and at least one group selected from the group consisting of —X 2 —(C═X 4 )—X 3 —, —NR 5 —(SO 2 )—, —CO—NR 6 —CO—, —O—, —S—, —COOH, —CN, —NR 7 R 8 , —OH, and —SH per molecule.
• US9850356B2
  申请人：——

  公开号：US9850356B2

  公开（公告）日：2017-12-26