N-stearoyl-L-glutamic acid diethyl ester | 14379-62-5

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: N-stearoyl-L-glutamic acid diethyl ester
• 英文别名: N-Stearyl-L-glutaminsaeure-diaethylester；N-stearoyl-L-glutamic acid diethyl ester；N-Stearoyl-L-glutaminsaeure-diaethylester
• CAS: 14379-62-5
• 化学式: C₂₇H₅₁NO₅
• 分子量: 469.706
• InChiKey: MXQIOENXSQFWFR-DEOSSOPVSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  6.64
• 重原子数：
  33.0
• 可旋转键数：
  23.0
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.89
• 拓扑面积：
  81.7
• 氢给体数：
  1.0
• 氢受体数：
  5.0

反应信息

• 作为反应物：
  描述：

  N-stearoyl-L-glutamic acid diethyl ester 在 sodium hydroxide 作用下， 以 甲醇 为溶剂， 生成 硬脂酰谷氨酸
  参考文献：
  名称：

  Inter- and intra-molecular H-bonds induced different nanostructures from a multi-H-bonding (MHB) amphiphile: nanofibers and nanodisksElectronic supplementary information (ESI) available: experimental data, AFM, SEM images, XRD, FT-IR and CD spectra of gels I and II, and molecular models. See http://www.rsc.org/suppdata/cc/b4/b402956a/

  摘要：

  N-stearoyl-L-glutamic acid（C18-Glu）是一种 MHB 两性化合物，由于分子间和分子内的 H 键作用，可在亲水和疏水环境中分别形成盘状和纤维状纳米结构。

  DOI：

  10.1039/b402956a
• 作为产物：
  描述：

  L-谷氨酸二乙酯盐酸盐 、 硬脂酸 生成 N-stearoyl-L-glutamic acid diethyl ester
  参考文献：
  名称：

  Inter- and intra-molecular H-bonds induced different nanostructures from a multi-H-bonding (MHB) amphiphile: nanofibers and nanodisksElectronic supplementary information (ESI) available: experimental data, AFM, SEM images, XRD, FT-IR and CD spectra of gels I and II, and molecular models. See http://www.rsc.org/suppdata/cc/b4/b402956a/

  摘要：

  N-stearoyl-L-glutamic acid（C18-Glu）是一种 MHB 两性化合物，由于分子间和分子内的 H 键作用，可在亲水和疏水环境中分别形成盘状和纤维状纳米结构。

  DOI：

  10.1039/b402956a

文献信息

• Amide–triazole isosteric substitution for tuning self-assembly and incorporating new functions into soft supramolecular materials
  作者：Jürgen Bachl、Judith Mayr、Francisco J. Sayago、Carlos Cativiela、David Díaz Díaz

  DOI：10.1039/c4cc08593k

  日期：——

  We report the proof-of-concept demonstration for the synthesis of novel supramolecular soft gel materials based on amide–triazole isometric substitution.

  我们报道了一种基于酰胺-三唑异构取代的新型超分子软凝胶材料合成的概念验证演示。
• Regulation of the Chiral Twist and Supramolecular Chirality in Co-Assemblies of Amphiphilic L-Glutamic Acid with Bipyridines
  作者：Xuefeng Zhu、Pengfei Duan、Li Zhang、Minghua Liu

  DOI：10.1002/chem.201002595

  日期：2011.3.14

  π–π stacking, hydrophobic, and chiral interactions is responsible for the formation of the chiral twists. An interesting sandwich structure, in which an excess of 4,4′‐bipyridine is inserted into the space of primary cages constructed from the amphiphile and 4,4′‐bipyridine, is proposed. Remarkably, the handedness of these chiral twists is related not only to the chiral center of the glutamic unit, but

  一系列两亲L‐glutamic acid derivatives with various saturated alkyl chains has been designed and their co‐assembly with 4,4′‐bipyridine in aqueous media has been investigated. While the individual amphiphiles formed hydrogels with water and self‐assembled into fine fiber networks, the addition of 4,4′‐bipyridine caused significant changes in the co‐assembled nanostructures such that twisted chiral ribbons
• Zeelen; Havinga, Recueil des Travaux Chimiques des Pays-Bas, 1958, vol. 77, p. 267,271
  作者：Zeelen、Havinga

  DOI：——

  日期：——