Epinephrine and lidocaine | 54958-67-7

• 分子结构分类: 有机化合物 - 有机杂环化合物
• 英文名称: Epinephrine and lidocaine
• 英文别名: 2-(diethylamino)-N-(2,6-dimethylphenyl)acetamide;4-[(1R)-1-hydroxy-2-(methylamino)ethyl]benzene-1,2-diol
• CAS: 54958-67-7
• 化学式: C23H35N3O4
• 分子量: 417.5
• InChiKey: HYKGUEIYMKVUSR-NPULLEENSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.93
• 重原子数：
  30
• 可旋转键数：
  8
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.43
• 拓扑面积：
  105
• 氢给体数：
  5
• 氢受体数：
  6

文献信息

• Electrically assisted lidocaine and epinephrine delivery device having extended shelf-stability
  申请人：Vyteris, Inc.

  公开号：EP1586347A1

  公开（公告）日：2005-10-19

  Highly shelf-stable electrically assisted transdermal drug delivery systems for deliverir g epinephrine, typically with an anesthetic such as lidocaine, are provided along with methods for making the highly shelf-stable epinephrine-containing transdermal deliver device. Highly shelf-stable packaged electrode assemblies for transdermal delivery of epinephrine also are provided.

  提供了用于输送肾上腺素（通常与利多卡因等麻醉剂一起）的高货架稳定性电辅助透皮给药系统，以及制造高货架稳定性含肾上腺素透皮给药装置的方法。还提供了用于透皮给药肾上腺素的高货架稳定性包装电极组件。
• System and method for surgical enhancement of the lips
  申请人：——

  公开号：US20030120307A1

  公开（公告）日：2003-06-26

  In a surgical technique for augmentation of the lips, first and second openings are made on a lip. An implant inserting tool is inserted into the first opening and routed through the lip to and out of the second opening. The tool grabs or clamps onto an implant. The tool is then withdrawn back out through the first opening. The implant is released from the tool, with the implant remaining in the lip. The ends of the implant are trimmed and the openings closed with sutures. The surgical technique and tool minimize the risk of bruising or possible hematoma, reduces pain and trauma and allows for faster recovery. Similar techniques and tools may be used to treat skin depressions caused by acne scarring, and for treating nasal labial folds.

  在一种丰唇手术技术中，要在嘴唇上开出第一和第二开口。将植入物插入工具插入第一开口，并穿过嘴唇到达第二开口，然后从第二开口出来。工具抓住或夹住植入物。然后将工具从第一个开口抽出。种植体从工具中脱出，但仍留在唇部。修剪种植体的末端，并缝合开口。这种手术技术和工具最大程度地降低了瘀伤或可能出现血肿的风险，减少了疼痛和创伤，使患者恢复更快。类似的技术和工具还可用于治疗痤疮疤痕造成的皮肤凹陷以及鼻唇沟。
• Physical, structural, mechanical, electrical and electromechanical features for use in association with electrically assisted delivery devices and systems
  申请人：Reddy NRK Vilambi

  公开号：US20050228335A1

  公开（公告）日：2005-10-13

  Provided are various embodiments of integrated electrode devices, assemblies and systems structured for use in association with electrically assisted delivery devices configured for delivery of a composition to a membrane. The integrated electrode devices, assemblies and systems include one or more of a variety of structural, physical, mechanical, electrical and electromechanical enhancements.

  本文提供了集成电极装置、组件和系统的各种实施方案，这些装置、组件和系统在结构上可与用于向膜输送组合物的电辅助输送装置配合使用。集成电极装置、组件和系统包括各种结构、物理、机械、电气和机电改进中的一种或多种。
• BIOMATERIAL COMPOSITION AND METHOD FOR PREPARING SAME
  申请人：CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS)

  公开号：EP0692986A1

  公开（公告）日：1996-01-24
• COMPOSITION POUR BIO-MATERIAU; PROCEDE DE PREPARATION
  申请人：CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS)

  公开号：EP0692986B1

  公开（公告）日：2000-07-19