1,3-Dibenzyl-benzimidazolium | 87963-21-1

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯并咪唑类
• 英文名称: 1,3-Dibenzyl-benzimidazolium
• 英文别名: 1,3-Dibenzylbenzimidazol-3-ium
• CAS: 87963-21-1
• 化学式: C₂₁H₁₉N₂
• 分子量: 299.395
• InChiKey: OBWKXPVNIZSKAN-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.8
• 重原子数：
  23
• 可旋转键数：
  4
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.1
• 拓扑面积：
  8.8
• 氢给体数：
  0
• 氢受体数：
  0

反应信息

• 作为反应物：
  描述：

  1,3-Dibenzyl-benzimidazolium 、 硫代异氰酸苯酯 在 sodium hydride 作用下， 生成 1,3-dibenzyl-2-N-phenylthiocarbamoylbenzimidazolium inner salt
  参考文献：
  名称：

  N杂环衍生的1,3-偶极与甲氧羰基丙二烯相互作用的实验和理论研究：受1,3-偶极N-杂环结构控制的高区域和立体选择性[3 + 2]-环加成反应

  摘要：

  通过实验和理论方法系统地研究了N-杂环卡宾衍生的1,3-偶极与甲氧羰基烯丙基的反应。1,3-偶极的[3 + 2]环加成对甲氧基羰基亚烷基的酯取代的（活化的）或烷基取代的（活性较低的）碳-碳双键的区域选择性强烈地受N杂环结构的支配。 1,3-偶极子。另外，在某些情况下，反应温度在调节[3 + 2]-环加成的区域选择性中起重要作用。而苯并咪唑卡宾衍生的2-硫代氨基甲酰基苯并咪唑内盐5和甲氧羰基烯丙基6之间的反应加热或不加热，得到的C主要加合物+ -C-S -部分与methoxycarbonylallenes的烷基取代的双键，三唑卡宾衍生的三唑盐14后行主要是C的其[3 + 2] -环+ -C-S -甲氧基羰基烯丙基的酯取代的双键的偶极子。在咪唑啉的情况下，碳烯衍生的1,3-偶极子10中，C之间发生的环加成+ -C-S -片段，在室温下活化的双键，而在回流的苯，但是，在相同的反应，得到从cycloadducts

  DOI：

  10.1021/jo802687m

文献信息

• Synthesis of chromium N-heterocyclic carbene complexes using chromium Fischer carbenes as a source of chromium carbonyls
  作者：Seongjin Kim、Soo Young Choi、Young Tak Lee、Kang Hyun Park、Helmut Sitzmann、Young Keun Chung

  DOI：10.1016/j.jorganchem.2007.08.043

  日期：2007.11

  Chromium Fischer carbene complexes, [CrOMe(R)}(CO)5] have been utilized as a source of chromium carbonyls in the synthesis of chromium NHC complexes. Using the synthetic method, chromium complexes of various NHC ligands were isolated in reasonable yields. Moreover, the method can be employed for the synthesis of molybdenum and tungsten NHC compounds.

  铬费歇尔卡宾络合物[Cr OMe（R）}（CO）5 ]已被用作铬NHC络合物的合成中的羰基铬源。使用合成方法，可以合理的产率分离出各种NHC配体的铬配合物。此外，该方法可用于合成钼和钨NHC化合物。
• Methods of Forming Carbene-Functionalized Composite Materials
  申请人：Queen's University at Kingston

  公开号：US20190169132A1

  公开（公告）日：2019-06-06

  Deposition of carbene monolayers that excluded starting anions, such as iodide ions, has been achieved. Anions such as iodide are a typical contaminant in carbene hydrogen carbonate salts when synthesized using the state-of-the-art method. A method is described for eliminating substantially all starting anion (e.g., iodide) contamination from the monolayer. Air stable, purified carbenes precursors were used to deposit an intact monolayer on the surface of some industrially relevant metals. The monolayer's ability to protect these metals against, for example, oxidation has been demonstrated.

  已经实现了排除起始阴离子（如碘离子）的卡宾单分子沉积。当使用最先进的方法合成卡宾氢碳酸盐时，碘离子等阴离子是典型的污染物。描述了一种方法，用于从单分子中消除几乎所有起始阴离子（例如碘）的污染。使用空气稳定、纯化的卡宾前体沉积在一些工业相关金属表面上形成完整的单分子层。已经证明了这种单分子层保护这些金属免受氧化等影响的能力。
• Methods of forming carbene-functionalized composite materials
  申请人：Queen's University at Kingston

  公开号：US11008291B2

  公开（公告）日：2021-05-18

  Deposition of carbene monolayers that excluded starting anions, such as iodide ions, has been achieved. Anions such as iodide are a typical contaminant in carbene hydrogen carbonate salts when synthesized using the state-of-the-art method. A method is described for eliminating substantially all starting anion (e.g., iodide) contamination from the monolayer. Air stable, purified carbenes precursors were used to deposit an intact monolayer on the surface of some industrially relevant metals. The monolayer's ability to protect these metals against, for example, oxidation has been demonstrated.

  实现了碳烯单层的沉积，排除了碘离子等起始阴离子。使用最先进的方法合成碳烯碳酸氢盐时，碘离子等阴离子是典型的污染物。本文介绍了一种从单层中基本消除所有起始阴离子（如碘离子）污染的方法。使用空气稳定的纯化碳烯前驱体在一些工业相关金属表面沉积完整的单层。该单层具有保护这些金属免受氧化等的能力。
• POLY-N-HETEROCYCLIC CARBENE TRANSITION METAL COMPLEXES AND N-HETEROCYCLIC CARBENE TRANSITION METAL COMPLEXES FOR CARBON-SULFUR AND CARBON-OXYGEN COUPLING REACTIONS
  申请人：Zhang Yugen

  公开号：US20100137608A1

  公开（公告）日：2010-06-03

  Methods for carbon-sulfur (C—S) or carbon-oxygen (C—O) coupling reactions are provided. The methods involve the use of a transition metal complex comprising a heterocyclic carbene ligand complexed with a transition metal. Transition metal complexes comprising a heterocyclic carbene ligand complexed with nickel are also provided. The nickel heterocylic carbene complexes may be used for C—S or C—O coupling reactions.
• METHOD FOR TREATING FIBROSIS AND CANCER WITH IMIDAZOLIUM AND IMIDAZOLINIUM COMPOUNDS
  申请人：Zhuo Lang

  公开号：US20110178040A1

  公开（公告）日：2011-07-21

  There is presently provided methods for delivering an anti-fibrotic or anti-cancer agent to a cell. The methods comprise contacting a cell with an effective amount of imidazolium and imidazolinium compounds as described herein, including imidazolium and imidazolinium salts.