1,8-bis(diphenylphosphino)-3,6-dimethylcarbazole | 1194952-79-8

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 1,8-bis(diphenylphosphino)-3,6-dimethylcarbazole
• 英文别名: (8-diphenylphosphanyl-3,6-dimethyl-9H-carbazol-1-yl)-diphenylphosphane
• CAS: 1194952-79-8
• 化学式: C₃₈H₃₁NP₂
• 分子量: 563.618
• InChiKey: FKWTUVPAJHBKTJ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  9.5
• 重原子数：
  41
• 可旋转键数：
  6
• 环数：
  7.0
• sp3杂化的碳原子比例：
  0.05
• 拓扑面积：
  15.8
• 氢给体数：
  1
• 氢受体数：
  0

反应信息

• 作为反应物：
  描述：

  1,8-bis(diphenylphosphino)-3,6-dimethylcarbazole 在 正丁基锂 作用下， 以 正己烷 、 正庚烷 、 甲苯 为溶剂， 反应 26.17h， 生成
  参考文献：
  名称：

  Yttrium and scandium complexes of a bulky bis(phosphinimine)carbazole ligand

  摘要：

  The synthesis and reactivity of a bulky bis(phosphinimine) carbazole pincer ligand (HL) bearing mesityl N-aryl groups is described. Reaction of HL with Y(CH2SiMe3)(3)(THF)(2) afforded a doubly cyclometalated organoyttrium complex, whereby the ligand was k(3)N, k(2)C coordinated to the metal via three nitrogen atoms and two ortho-metalated P-phenyl rings. Deprotonation of (HL) with (BuLi)-Bu-n liberated a monomeric and thermally stable lithium salt of the ligand (LLi). Salt metathesis reactions of LLi with ScCl3(THF)(3) and YCl3(THF)(3.5) generated the corresponding rare earth dichloro complexes, which were found to be monomeric and Lewis-base free. (C) 2014 Elsevier B. V. All rights reserved.

  DOI：

  10.1016/j.ica.2014.05.045
• 作为产物：
  描述：

  1,8,9-N-tris(diphenylphosphino)-3,6-dimethylcarbazole 在 三乙基铵碘化物 作用下， 以 二氯甲烷 为溶剂， 生成 1,8-bis(diphenylphosphino)-3,6-dimethylcarbazole
  参考文献：
  名称：

  Yttrium and scandium complexes of a bulky bis(phosphinimine)carbazole ligand

  摘要：

  The synthesis and reactivity of a bulky bis(phosphinimine) carbazole pincer ligand (HL) bearing mesityl N-aryl groups is described. Reaction of HL with Y(CH2SiMe3)(3)(THF)(2) afforded a doubly cyclometalated organoyttrium complex, whereby the ligand was k(3)N, k(2)C coordinated to the metal via three nitrogen atoms and two ortho-metalated P-phenyl rings. Deprotonation of (HL) with (BuLi)-Bu-n liberated a monomeric and thermally stable lithium salt of the ligand (LLi). Salt metathesis reactions of LLi with ScCl3(THF)(3) and YCl3(THF)(3.5) generated the corresponding rare earth dichloro complexes, which were found to be monomeric and Lewis-base free. (C) 2014 Elsevier B. V. All rights reserved.

  DOI：

  10.1016/j.ica.2014.05.045

文献信息

• Organolutetium-Mediated Dearomatization and Functionalization of Pyrimidine Rings
  作者：Kevin R. D. Johnson、Paul G. Hayes

  DOI：10.1021/om400413e

  日期：2013.8.12

  The synthesis of a pentadentate NNNNN bis(phosphinimine)carbazole pincer ligand bearing two pyrimidine N-aryl rings is reported. A dialkyl lutetium complex of the ligand, prepared by alkane elimination with Lu-(CH2SiMe3)(3)(THF)(2), was found to undergo an unusual transformation involving a double alkyl shift whereby the -CH2SiMe3 groups on the metal migrated to both pyrimidine rings. This migration afforded a final product that featured alkyl-functionalized, dearomatized ligand pyrimidine rings.