[(stearoyloxy)methyl]propyl stearate | 33599-13-2

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: [(stearoyloxy)methyl]propyl stearate
• 英文别名: 1,2-butylene glycol distearate；3-butylene glycol distearate；1,2-butanediol distearate；2-octadecanoyloxybutyl octadecanoate
• CAS: 33599-13-2
• 化学式: C₄₀H₇₈O₄
• 分子量: 623.057
• InChiKey: PVRMECYYHAHLCP-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  17.8
• 重原子数：
  44
• 可旋转键数：
  38
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.95
• 拓扑面积：
  52.6
• 氢给体数：
  0
• 氢受体数：
  4

文献信息

• ENCAPSULATING SYSTEM FOR CEST IMAGING WITH CHELATE Q GREATER THAN OR EQUAL TO 2
  申请人：Port Marc

  公开号：US20110243859A1

  公开（公告）日：2011-10-06

  The present invention relates to the use of a CEST contrast agent in a method of CEST imaging, wherein the contrast agent is a composition comprising an encapsulating system ES encapsulating at least one CEST agent, wherein the at least one CEST agent is constituted of a monomeric chelate of a chelate of q≧2 type, or of a multimer of monomeric chelates of q≧2 type, and wherein said chelate is free inside the encapsulating system.
• COMPOSITIONS AND METHODS FOR DELIVERY OF AGENTS
  申请人：ModernaTX, Inc.

  公开号：US20180028664A1

  公开（公告）日：2018-02-01

  This disclosure provides improved lipid-based compositions, including lipid nanoparticle compositions, and methods of use thereof for delivering agents in vivo including nucleic acids and proteins. These compositions are not subject to accelerated blood clearance and they have an improved toxicity profile in vivo.