tetramethylguanidinium trichloroacetate | 38493-99-1

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: tetramethylguanidinium trichloroacetate
• 英文别名: [Amino(dimethylamino)methylidene]-dimethylazanium;2,2,2-trichloroacetate；[amino(dimethylamino)methylidene]-dimethylazanium;2,2,2-trichloroacetate
• CAS: 38493-99-1
• 化学式: C₂HCl₃O₂*C₅H₁₃N₃
• 分子量: 278.566
• InChiKey: ZJJSIXNQCAABKT-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.49
• 重原子数：
  15
• 可旋转键数：
  2
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.71
• 拓扑面积：
  67.6
• 氢给体数：
  2
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  四甲基胍 、 三氯乙酸 以 甲醇 为溶剂， 反应 48.0h， 生成 tetramethylguanidinium trichloroacetate
  参考文献：
  名称：

  集成的高通量策略可发现用于可持续化学过程的多功能离子液体

  摘要：

  开发具有简化的反应系统和后处理程序的新化学工艺是一项艰巨的任务。尽管离子液体是简化传统化学过程的一类潜在的多功能化合物，但是由于复杂的相互作用，它们的合理设计仍然很困难。在这项工作中，提出了一种概念验证策略，以实现离子液体的高通量制备和原位集成。在96孔板中筛选其促进反应的性能。然后，该集成方法可以轻松地从400个离子液体候选物库中识别出最佳离子液体，以同时充当羰基叠氮化物环加成反应的溶剂，催化剂和分离助剂。基于离子液体的方法的优点不仅在方便，高效地合成1,2,3-三唑基化合物中得到了证明，而且还在发现用于化学后修饰游离肽的新反应的过程中得到了证明。

  DOI：

  10.1039/c8gc03119c

文献信息

• Processes, products, and compositions having tetraalkylguanidine salt of aromatic carboxylic acid
  申请人：EVONIK DEGUSSA GMBH

  公开号：US10464876B2

  公开（公告）日：2019-11-05

  Disclosed are processes, products, and compositions having tetraalkylguanidine salt of aromatic acid. The processes include providing a pre-mix comprising an aromatic carboxylic acid component and contacting a tetraalkylguanidine with the aromatic carboxylic acid component in the pre-mix to form the tetraalkylguanidine salt of aromatic carboxylic acid or producing a catalyst composition by contacting the tetraalkylguanidine with the aromatic carboxylic acid component to form the tetraalkylguanidine salt of aromatic carboxylic acid. The compositions include the tetraalkylguanidine salt of aromatic carboxylic acid. The product is formed by the tetraalkylguanidine salt of aromatic carboxylic acid.

  公开了具有芳香酸四烷基胍盐的工艺、产品和组合物。这些工艺包括提供包含芳香族羧酸组分的预混料，并将四烷基胍与预混料中的芳香族羧酸组分接触，形成芳香族羧酸的四烷基胍盐，或通过将四烷基胍与芳香族羧酸组分接触，形成芳香族羧酸的四烷基胍盐，生产催化剂组合物。组合物包括芳香族羧酸四烷基胍盐。产品由芳香族羧酸四烷基胍盐形成。
• Delay action catalyst for improving the stability of polyurethane systems having halogen containing blowing agents
  申请人：Evonik Operations GmbH

  公开号：EP2725047B1

  公开（公告）日：2020-12-16
• PROCESSES, PRODUCTS, AND COMPOSITIONS HAVING TETRAALKYLGUANIDINE SALT OF AROMATIC CARBOXYLIC ACID
  申请人：Air Products and Chemicals, Inc.

  公开号：EP2780385A1

  公开（公告）日：2014-09-24
• Processes, Products, and Compositions Having Tetraalkylguanidine Salt of Aromatic Carboxylic Acid
  申请人：Air Products and Chemicals, Inc.

  公开号：US20130131276A1

  公开（公告）日：2013-05-23

  Disclosed are processes, products, and compositions having tetraalkylguanidine salt of aromatic acid. The processes include providing a pre-mix comprising an aromatic carboxylic acid component and contacting a tetraalkylguanidine with the aromatic carboxylic acid component in the pre-mix to form the tetraalkylguanidine salt of aromatic carboxylic acid or producing a catalyst composition by contacting the tetraalkylguanidine with the aromatic carboxylic acid component to form the tetraalkylguanidine salt of aromatic carboxylic acid. The compositions include the tetraalkylguanidine salt of aromatic carboxylic acid. The product is formed by the tetraalkylguanidine salt of aromatic carboxylic acid.
• Delay Action Catalyst for Improving The Stability of Polyurethane Systems Having Halogen Containing Blowing Agents
  申请人：AIR PRODUCTS AND CHEMICALS, INC.

  公开号：US20140113984A1

  公开（公告）日：2014-04-24

  Catalyst compositions useful in the production of insulating polyurethane or polyisocyanurate foam are disclosed. The catalyst compositions impart increased stability of a mixture of the catalyst, a halogen-containing blowing agent, and a polyol. These catalyst compositions include amine/acid salts with a pH of <7.0 which can be used in combined with tertiary amine catalysts and metal-based or ammonium-based trimerization catalyst and at least one metal-based gel catalyst and optionally one or more of an additional catalyst described in (1) or (2). These improved catalysts can be used with any halogenated blowing agent, and provide substantial stability benefits with the use of hydrofluoroolefins and hydrofluorochloroolefins. In an exemplary embodiment, a process includes providing a pre-mix comprising an organic carboxylic di-acid, tri-acid or poly-acid component and contacting a tetraalkylguanidine and/or a tertiary amine containing an isocyanate reactive group with the acid component in the pre-mix to form a mixture of tetraalkylguanidine salt or tertiary amine salt or their combination.