3-Acetoxymethyl-8-oxo-7-[(thiophene-2-carbonyl)-amino]-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid | 104758-14-7

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: 3-Acetoxymethyl-8-oxo-7-[(thiophene-2-carbonyl)-amino]-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid
• 英文别名: 3-(Acetyloxymethyl)-8-oxo-7-(thiophene-2-carbonylamino)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
• CAS: 104758-14-7
• 化学式: C₁₅H₁₄N₂O₆S₂
• 分子量: 382.418
• InChiKey: WLBZMMUMCZCQKL-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.2
• 重原子数：
  25
• 可旋转键数：
  6
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.33
• 拓扑面积：
  167
• 氢给体数：
  2
• 氢受体数：
  8

文献信息

• PHOTOACTIVATABLE ANTIMICROBIAL AGENTS AND THERAPEUTIC AND DIAGNOSTIC METHODS OF USING SAME
  申请人：Hasan Tayyaba

  公开号：US20110112059A1

  公开（公告）日：2011-05-12

  The present invention provides photosensitizer compounds for use in detecting beta-lactamase activity. Methods and kits that utilize the photosensitizer compounds of the invention for the detection of, quantitation of, and classification or typing of microbial beta-lactamases.

  本发明提供了用于检测β-内酰胺酶活性的光敏剂化合物。利用本发明的光敏剂化合物进行微生物β-内酰胺酶的检测、定量和分类或分型的方法和试剂盒。
• PHOTOACTIVATABLE ANTIMICROBIAL AGENTS
  申请人：Hasan Tayyaba

  公开号：US20100016208A1

  公开（公告）日：2010-01-21

  Photoactivatable antimicrobial compounds and methods for the use thereof in the treatment of infections are provided.
• BETA-LACTAMASE TARGETED PHOTOSENSITIZER FOR PESTICIDE AND PEST DETECTION
  申请人：The General Hospital Corporation

  公开号：US20160073634A1

  公开（公告）日：2016-03-17

  Photoactivatable pesticide compounds and methods for the use thereof in the elimination and detection of pests are provided.
• DETECTING TARGETS USING MASS TAGS AND MASS SPECTROMETRY
  申请人：Ventana Medical Systems, Inc.

  公开号：US20160139143A1

  公开（公告）日：2016-05-19

  Particular disclosed embodiments disclosed herein concern using a one or more various mass tags, which can be specifically deposited at targets through direct or indirect enzymatic-catalyzed transformation, to provide a method for identifying targets in tissue samples. The mass tags may be labeled with stable isotopes to produce mass tags having the same chemical structure but different masses. Mass codes produced by ionizing the mass tags are detected and/or quantified using mass spectrometry. The method can be used for multiplexed detection of multiple targets in a particular sample. In some embodiments, a map divided into sections representing sections of the tissue sample may be prepared, with the map sections including data corresponding to quantification data wherein the size of a mass peak is determined and correlated with the amount of a target for the corresponding tissue sample section.
• US9291597B2
  申请人：——

  公开号：US9291597B2

  公开（公告）日：2016-03-22