N-2-ethylhexyl-N-methyl-4-aminobenzoic acid | 113387-43-2

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: N-2-ethylhexyl-N-methyl-4-aminobenzoic acid
• 英文别名: 4-[2-Ethylhexyl(methyl)amino]benzoic acid
• CAS: 113387-43-2
• 化学式: C₁₆H₂₅NO₂
• 分子量: 263.38
• InChiKey: MXPHJDKQYGVPDQ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.7
• 重原子数：
  19
• 可旋转键数：
  8
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.56
• 拓扑面积：
  40.5
• 氢给体数：
  1
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  2,4-二羟二苯甲酮 、 4-(2-bromoethyl)-2,4-dihydroxybenzophenone 、 N-2-ethylhexyl-N-methyl-4-aminobenzoic acid 、 dimethyldioctyldecylammonium bromide 、 1,2-二溴乙烷 生成 (4-ethylene-2,4-dihydroxybenzophenone) N-2-ethylhexyl-N-methyl-4-aminobenzoate
  参考文献：
  名称：

  摘要：

  DOI：

文献信息

• Novel chromophores, sunscreen compositions and methods for preventing sunburn
  申请人：THE PROCTER & GAMBLE COMPANY

  公开号：EP0251398A2

  公开（公告）日：1988-01-07

  The present invention relates to novel chromophore-containing compounds useful as sunscreen agents which have the ability to absorb both UVA and UVB wavelength radiation. These compounds comprise a specific type of UVA-absorbing chromophore covalently bonded to a specific type of UVB-absorbing chromophore. The chromophore moieties are covalently bonded together such that the electron systems of these moieties are directly coupled to thereby form a new chromophore. The present invention further relates to sunscreen compositions containing the hereinbefore described type of sunscreen agents. Furthermore, the present invention relates to methods for protecting the skin of humans or lower animals from the effects of UVA and UVB wavelength radiation. This method comprises topically applying to the skin an effective coating of a sunscreen composition of the present invention.

  本发明涉及可用作防晒剂的新型含发色团化合物，这些化合物具有吸收 UVA 和 UVB 波长辐射的能力。这些化合物由一种特定类型的吸收 UVA 的发色团与一种特定类型的吸收 UVB 的发色团共价键合而成。发色团分子共价键合在一起，使这些分子的电子系统直接耦合，从而形成新的发色团。 本发明还涉及含有上述类型防晒剂的防晒组合物。此外，本发明还涉及保护人类或低等动物皮肤免受 UVA 和 UVB 波长辐射影响的方法。该方法包括在皮肤上局部涂抹本发明防晒组合物的有效涂层。
• Novel sunscreen agents, sunscreen compositions and methods for preventing sunburn
  申请人：THE PROCTER & GAMBLE COMPANY

  公开号：EP0255157A2

  公开（公告）日：1988-02-03

  The present invention relates to novel sunscreen agents which have the ability to absorb both UVA and UVB wavelength radiation. The sunscreen agents comprise a specific type of UVA-absorbing chromophore covalently bonded to a specific type of UVB-absorbing chromophore. The chromophore moieties are covalently bonded together such that the electron systems of these moieties are not directly coupled. The present invention further relates to sunscreen com­positions containing the hereinbefore described type of sunscreen agents. Furthermore, the present invention relates to methods for protecting the skin of humans or lower animals from the effects of UVA and UVB wavelength radiation. This method comprises topically applying to the skin an effective coating of a sunscreen composition of the present invention.

  本发明涉及新型防晒剂，这种防晒剂具有吸收 UVA 和 UVB 波长辐射的能力。这种防晒剂由一种特定类型的吸收 UVA 的发色团与一种特定类型的吸收 UVB 的发色团共价键合而成。发色团分子共价键合在一起，使这些分子的电子系统不直接耦合。 本发明还涉及含有上述类型防晒剂的防晒组合物。此外，本发明还涉及保护人类或低等动物皮肤免受 UVA 和 UVB 波长辐射影响的方法。该方法包括在皮肤上局部涂抹本发明防晒组合物的有效涂层。
• US4937370A
  申请人：——

  公开号：US4937370A

  公开（公告）日：1990-06-26
• US4999186A
  申请人：——

  公开号：US4999186A

  公开（公告）日：1991-03-12
• US5041282A
  申请人：——

  公开号：US5041282A

  公开（公告）日：1991-08-20