hydroxypolyethylene glycol methacrylate | 398140-49-3

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: hydroxypolyethylene glycol methacrylate
• 英文别名: Glykolmetakrylat；1,2-dihydroxyethyl 2-methylprop-2-enoate
• CAS: 398140-49-3
• 化学式: C₆H₁₀O₄
• 分子量: 146.143
• InChiKey: RIWPJGYFWKUIER-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.2
• 重原子数：
  10
• 可旋转键数：
  4
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.5
• 拓扑面积：
  66.8
• 氢给体数：
  2
• 氢受体数：
  4

文献信息

• SULFONIUM COMPOUNDS, THEIR PREPARATION AND USE
  申请人：BASF SE

  公开号：US20150044509A1

  公开（公告）日：2015-02-12

  Compounds of the formula (I), (Ia) or (Ib) wherein A 1 , and A − is for example (II) is 1 or 2; X is C 1 -C 4 alkylene or CO; Y is for example O, O(CO), O(CO)O, R 1 is for example hydrogen, d-dsalkyl, C 3 -C 30 cycloalkyl, phenyl, naphthyl, anthracyl, phenanthryl, biphenylyl, fluorenyl or C 3 -C 20 heteroaryl, all of which optionally are substituted; R 2 and R 3 for example are C 1 -C 10 haloalkylene which is optionally substituted, or R 2 and R 3 are phenylene, which optionally is substituted; R 4 is a group (A) or a group (B); R 5 and R 6 for example are C 1 -C 20 alkyl; or R 4 and R 5 or R 4 and R 6 together form a straight-chain C 2 -C 6 alkylene, R 5 and R 6 together form a straight-chain C 2 -C 6 alkylene; R 7 , R 8 , R 9 and R 10 ifor example are C 1 -C 20 alkyl; M for example is C 1 -C 20 alkylene, C 2 -C 20 alkenylene, C 2 -C 20 alkynylene; R 25 and R 26 are for example hydrogen, C 1 -C 20 alkyl; R 27 , R 28 , R 29 , R 30 and R 31 are for example hydrogen, C 1 -C 20 alkyl, C 2 -C 20 alkenyl, C 3 -C 20 cycloalkyl, or two radicals R 27 and R 28 , R 28 and R 29 , R 29 and R 30 and/or R 30 and R 31 together form a straight-chain C 2 -C 6 alkylene, or R 25 and R 27 together form 1,2-phenylene, R 33 and R 34 for example are hydrogen, C 1 -C 20 alkyl; R 35 , R 36 and R 37 for example are hydrogen, C 1 -C 20 alkyl; are suitable as thermo-acid generators.

  化合物的公式(I)、(Ia)或(Ib)，其中A1和A-例如(II)为1或2；X为C1-C4烷基或CO；Y例如为O、O(CO)、O(CO)O、R1例如为氢、d-ds烷基、C3-C30环烷基、苯基、萘基、蒽基、菲基、联苯基、芴基或C3-C20杂环芳基，全部可选地被取代；R2和R3例如为可选地被取代的C1-C10卤代烷基，或R2和R3为苯基，可选地被取代；R4为(A)基团或(B)基团；R5和R6例如为C1-C20烷基；或R4和R5或R4和R6一起形成直链C2-C6烷基，R5和R6一起形成直链C2-C6烷基；R7、R8、R9和R10例如为C1-C20烷基；M例如为C1-C20烷基、C2-C20烯基、C2-C20炔基；R25和R26例如为氢、C1-C20烷基；R27、R28、R29、R30和R31例如为氢、C1-C20烷基、C2-C20烯基、C3-C20环烷基，或两个基团R27和R28、R28和R29、R29和R30和/或R30和R31一起形成直链C2-C6烷基，或R25和R27一起形成1,2-苯基，R33和R34例如为氢、C1-C20烷基；R35、R36和R37例如为氢、C1-C20烷基；适用于热酸发生器。
• Molecular Healing of Polymeric Materials, Coatings, Plastics, Elastomers, Composites, Laminates, Adhesives, and Sealants by Active Enzymes
  申请人：McDaniel C. Steven

  公开号：US20100210745A1

  公开（公告）日：2010-08-19

  Disclosed herein are polymeric materials such as a coating, a plastic, a laminate, a composite, an elastomer, an adhesive, or a sealant; a surface treatment such as a textile finish or a wax; a filler for such a polymeric material or a surface treatment that includes an enzyme such as an esterase (e.g., a lipolytic enzyme, a sulfuric ester hydrolase, an organophosphorus compound degradation enzyme), an enzyme (e.g., a lysozyme, a lytic transglycosylase) that degrades a cell wall and/or a cell membrane component, a biocidal or biostatic peotide, and/or a peptidase. Also disclosed herein are methods of altering a material's property such as service life, flexability, or rigidity, by incorporation of an enzyme into a material capable of being chemically crosslinked by the activity of a lipolytic enzyme, a hydrolase, and/or a urease.

  本文公开了一些聚合材料，如涂层、塑料、层压板、复合材料、弹性体、粘合剂或密封剂；一种表面处理，如纺织品涂层或蜡；一种填料，用于这样的聚合材料或表面处理，其中包括一种酶，如酯酶（例如，脂肪水解酶，硫酸酯水解酶，有机磷化合物降解酶），降解细胞壁和/或细胞膜成分的酶（例如，溶菌酶，裂解转糖基酶），生物杀菌或生物静态肽，以及/或肽酶。本文还公开了通过将酶纳入可通过脂肪水解酶、水解酶和/或脲酶的活性交联材料中来改变材料性能，如使用寿命、柔韧性或刚度的方法。
• Anti-fouling Paints and Coatings
  申请人：Reactive Surfaces LTD

  公开号：US20150191607A1

  公开（公告）日：2015-07-09

  Disclosed herein are polymeric materials such as a coating, a plastic, a laminate, a composite, an elastomer, an adhesive, or a sealant; a surface treatment such as a textile finish or a wax; a filler for such a polymeric material or a surface treatment that includes an enzyme such as an esterase (e.g., a lipolytic enzyme, a sulfuric ester hydrolase, an organophosphorus compound degradation enzyme), an enzyme (e.g., a lysozyme, a lytic transglycosylase) that degrades a cell wall and/or a cell membrane component, a biocidal or biostatic peptide, and/or a peptidase. Also disclosed herein are methods of altering a material's property such as service life, flexability, or rigidity, by incorporation of an enzyme into a material capable of being chemically crosslinked by the activity of a lipolytic enzyme, a hydrolase, and/or a urease.

  本文披露了聚合材料，例如涂层、塑料、层压材料、复合材料、弹性体、粘合剂或密封剂；表面处理，例如纺织品整理或蜡；填充剂，用于这种聚合材料或表面处理，包括酯酶（例如脂肪水解酶、硫酸酯水解酶、有机磷化合物降解酶）的酶，降解细胞壁和/或细胞膜成分的酶（例如溶菌酶、裂解转葡糖苷酶），生物杀菌或生物稳定肽，和/或肽酶。本文还披露了通过将酶并入能够通过脂肪水解酶、水解酶和/或脲酶的活性进行化学交联的材料中，改变材料性能（例如使用寿命、柔韧性或刚度）的方法。
• Optical coating composition
  申请人：E.I. DU PONT DE NEMOURS AND COMPANY

  公开号：EP0210638A2

  公开（公告）日：1987-02-04

  An optical coating composition comprising a C1-3 hydroxyalkyl monofunctional acrylate monomer having dissolved therein an oligomer having a molecular weight of at least 500 and a photoinitiator system.

  一种光学涂层组合物，由 C1-3 羟烷基单官能丙烯酸酯单体（其中溶解有分子量至少为 500 的低聚物）和光引发剂体系组成。
• Filter medium having a limited surface negative charge for treating a blood material
  申请人：ASAHI MEDICAL Co., Ltd.

  公开号：EP0561379A1

  公开（公告）日：1993-09-22

  Disclosed is a filter medium for treating a blood material selected from the group consisting of a leukocyte-containing suspension and plasma, comprising a polymeric, porous element having, in a surface portion thereof, a negative charge and having a surface electric charge of not smaller than -30 µeq/g of the polymeric, porous element. The filter medium and an apparatus having the filter medium packed in a casing having an inlet and an outlet, can be advantageously used for treating a blood material, for example, for separating leukocytes from a leukocyte-containing suspension including whole blood, for blood dialysis or for removing undesired proteinous substances and the like from whole blood or plasma by adsorption-filtration, while effectively controlling a concentration of bradykinin (which is causative of anaphylactic reactions) in a treated blood to a level not exceeding 4,000 pg/ml.

  本发明公开了一种用于处理选自含白细胞悬浮液和血浆组的血液材料的过滤介质，该过滤介质由聚合物多孔元件组成，聚合物多孔元件的表面部分带有负电荷，且聚合物多孔元件的表面电荷不小于-30 µeq/g。该过滤介质以及将该过滤介质装入具有入口和出口的套管中的装置，可以很好地用于处理血液材料，例如，从包括全血在内的含白细胞悬浮液中分离白细胞，用于血液透析，或通过吸附过滤从全血或血浆中去除不需要的蛋白质等物质，同时有效地将处理过的血液中缓激肽（导致过敏反应）的浓度控制在不超过 4,000 pg/ml 的水平。