1,1-dimethyl-2-<1-(3-isopropenyl-phenyl)-1-methyl-ethyl>-urea-N-4-chlorophenyl-carbamate | 151888-16-3

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 1,1-dimethyl-2-<1-(3-isopropenyl-phenyl)-1-methyl-ethyl>-urea-N-4-chlorophenyl-carbamate
• 英文别名: [2-methyl-1-[2-(3-prop-1-en-2-ylphenyl)propan-2-ylcarbamoylamino]propan-2-yl] N-(4-chlorophenyl)carbamate
• CAS: 151888-16-3
• 化学式: C₂₄H₃₀ClN₃O₃
• 分子量: 443.974
• InChiKey: XBBRBTSQYSYZBZ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.4
• 重原子数：
  31
• 可旋转键数：
  8
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.33
• 拓扑面积：
  79.5
• 氢给体数：
  3
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  甲基丙烯酸甲酯 、 1,1-dimethyl-2-<1-(3-isopropenyl-phenyl)-1-methyl-ethyl>-urea-N-4-chlorophenyl-carbamate 在 偶氮二异丁腈 作用下， 以 四氢呋喃 为溶剂， 反应 48.0h， 以95%的产率得到Poly <1,1-dimethyl-2-<1-(3-isopropenyl-phenyl)-1-methyl-ethyl>-urea-N-4-chlorophenyl-carbamate-co-methyl-methacrylate>
  参考文献：
  名称：

  Modified tert-butyloxycarbonyl(BOC) derivatives as new aminoprotecting groups

  摘要：

  Some novel low-molecular weight and polymerizable N-acylamino-modified BOC-type aminoprotecting groups are described. Deprotection with trifluoroacetic acid (TFA) and with HBr in acetic acid, which was followed by NMR spectroscopy, leads to the formation of 4,S-dihydro-oxazole derivatives. Reactivities and solubilities of the new compounds are controlled significantly by the N-acyl moiety.

  DOI：

  10.1016/s0040-4020(01)87972-2
• 作为产物：
  描述：

  3-异丙烯基-α,α-二甲基苄基异氰酸酯 在 dibutyltin(II) dilaurate 作用下， 以 乙酸乙酯 为溶剂， 反应 38.0h， 生成 1,1-dimethyl-2-<1-(3-isopropenyl-phenyl)-1-methyl-ethyl>-urea-N-4-chlorophenyl-carbamate
  参考文献：
  名称：

  Modified tert-butyloxycarbonyl(BOC) derivatives as new aminoprotecting groups

  摘要：

  Some novel low-molecular weight and polymerizable N-acylamino-modified BOC-type aminoprotecting groups are described. Deprotection with trifluoroacetic acid (TFA) and with HBr in acetic acid, which was followed by NMR spectroscopy, leads to the formation of 4,S-dihydro-oxazole derivatives. Reactivities and solubilities of the new compounds are controlled significantly by the N-acyl moiety.

  DOI：

  10.1016/s0040-4020(01)87972-2

文献信息

• Modified tert-butyloxycarbonyl(BOC) derivatives as new aminoprotecting groups
  作者：Marcus Gormanns、Helmut Ritter

  DOI：10.1016/s0040-4020(01)87972-2

  日期：1993.8

  Some novel low-molecular weight and polymerizable N-acylamino-modified BOC-type aminoprotecting groups are described. Deprotection with trifluoroacetic acid (TFA) and with HBr in acetic acid, which was followed by NMR spectroscopy, leads to the formation of 4,S-dihydro-oxazole derivatives. Reactivities and solubilities of the new compounds are controlled significantly by the N-acyl moiety.