2-(4-(9H-3,9′-bicarbazol-9-yl)phenyl)-1H-imidazo[4,5-f][1,10]phenanthroline | 1391865-53-4

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯并咪唑类
• 英文名称: 2-(4-(9H-3,9′-bicarbazol-9-yl)phenyl)-1H-imidazo[4,5-f][1,10]phenanthroline
• 英文别名: 2-[4-(3-carbazol-9-ylcarbazol-9-yl)phenyl]-1H-imidazo[4,5-f][1,10]phenanthroline
• CAS: 1391865-53-4
• 化学式: C₄₃H₂₆N₆
• 分子量: 626.72
• InChiKey: MFIFOXHAEDSVOZ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  9.8
• 重原子数：
  49
• 可旋转键数：
  3
• 环数：
  11.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  64.3
• 氢给体数：
  1
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  sodium perchlorate 、 cis-Ru(Bpy)2Cl2·2H2O 、 2-(4-(9H-3,9′-bicarbazol-9-yl)phenyl)-1H-imidazo[4,5-f][1,10]phenanthroline 以 乙醇 、 水 为溶剂， 反应 6.0h， 以50%的产率得到[Ru(bpy)₂(Hbcpip)](ClO₄)₂
  参考文献：
  名称：

  The effects of linear assembly of two carbazole groups on acid–base and DNA-binding properties of a ruthenium(II) complex

  摘要：

  A novel Ru(II) complex of [Ru(bpy)(2)(Hbcpip)](ClO4)(2) {where bpy = 2,2-bipyridine, Hbcpip = 2-(4-(9H-3,9'-bicarbazol-9-yl)phenyl)-1H-imidazo[4,5-f][1,10]phenanthroline} is synthesized and characterized. Calfthymus DNA-binding properties of the complex were studied by UV-vis absorption and luminescence titrations, steady-state emission quenching by [Fe(CN)(6)](4-), DNA competitive binding with ethidium bromide, thermal denaturation and DNA viscosity measurements. The results indicate that the complex partially intercalated into the DNA with a binding constant of (5.5 +/- 1.4) x 10(5) M-1 in buffered 50 mM NaCl. The acid-base properties of the complex were also studied by UV-visible and luminescence spectrophotometric pH titrations, and ground- and excited-state acidity ionization constant values were derived. (C) 2013 Elsevier B.V. All rights reserved.

  DOI：

  10.1016/j.saa.2013.04.017