1,14-bisformyl-5,10-diphenyl-16-thiatripyrromethane | 223921-73-1

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 1,14-bisformyl-5,10-diphenyl-16-thiatripyrromethane
• 英文别名: 5-[[5-[(5-formyl-1H-pyrrol-2-yl)-phenylmethyl]thiophen-2-yl]-phenylmethyl]-1H-pyrrole-2-carbaldehyde
• CAS: 223921-73-1
• 化学式: C₂₈H₂₂N₂O₂S
• 分子量: 450.561
• InChiKey: YPMHPHARCMUODI-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.7
• 重原子数：
  33
• 可旋转键数：
  8
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.07
• 拓扑面积：
  94
• 氢给体数：
  2
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  吡咯 、 1,14-bisformyl-5,10-diphenyl-16-thiatripyrromethane 在 三氟化硼乙醚 作用下， 以69%的产率得到tripyrrylmethane
  参考文献：
  名称：

  Synthesis of oligopyrrolic cluster bearing thiophene spacer as potential anion receptors

  摘要：

  The oligopyrrolic clusters and tripyrrylmethane have been synthesized and characterized by the utilization of 2-formylpyrroles and their derivatives as building blocks. Condensation of dialdehydes 9 with pyrrole in the presence of BF3(Et2O) resulted in the formation of tripyrrlymethane 10, while similar condensation performed in trifluoroacetic acid afforded oligopyrrolic cluster 11 on the other hand. The nature of substituents at meso-positions resulted in the formation of completely different products. (C) 2003 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/s0040-4039(03)01625-3
• 作为产物：
  描述：

  2,5-bis(α-hydroxy-α-phenylmethyl)thiophene 在 三氟化硼乙醚 、 三氯氧磷 作用下， 生成 1,14-bisformyl-5,10-diphenyl-16-thiatripyrromethane
  参考文献：
  名称：

  Synthesis of pseudoaromatic expanded porphyrin analogues

  摘要：

  Optically active expanded porphyrins bearing thiophene were synthesized by Schiff base forming reaction. The condensation of thiophene containing 1,14-bisformyl tripyrrane with aromatic diamines Failed to give desired macrocycles but condensation with aliphatic 1,2-diamines gave the desired products. The macrocycles synthesized tend to maintain 18 pi system and the ethylene bridge shows somewhat resistance toward oxidation. (C) 1999 Elsevier Science Ltd. All rights reserved.

  DOI：

  10.1016/s0040-4039(99)00044-1