N-allyl-N-(2-hydroxyphenyl)-4-methylbenzenesulfonamide | 1100730-10-6

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: N-allyl-N-(2-hydroxyphenyl)-4-methylbenzenesulfonamide
• 英文别名: N-(2-hydroxyphenyl)-4-methyl-N-prop-2-enylbenzenesulfonamide
• CAS: 1100730-10-6
• 化学式: C₁₆H₁₇NO₃S
• 分子量: 303.382
• InChiKey: PERYNDCECPYXBJ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.3
• 重原子数：
  21
• 可旋转键数：
  5
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.12
• 拓扑面积：
  66
• 氢给体数：
  1
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  烯丙基二甲基氯硅烷 、 N-allyl-N-(2-hydroxyphenyl)-4-methylbenzenesulfonamide 在 三乙胺 作用下， 以 二氯甲烷 为溶剂， 反应 15.0h， 以80%的产率得到N-allyl-N-(2-((allyldimethylsilyl)oxy)phenyl)-4-methylbenzenesulfonamide
  参考文献：
  名称：

  Ring-closing metathesis for the synthesis of novel 9- and 10-membered silicon-containing benzo-fused heterocycles

  摘要：

  A ring-closing metathesis (RCM) strategy afforded a number of novel 9- and 10-membered benzo-fused Compounds containing at least one silicon atom as part of the heterocyclic portion. In this manner, the following compounds containing heterocyclic rings of 9-10 atoms were synthesized: (Z)-2,2-dimethyl-7-[(4-methylphenyl)sulfonyl]-2,3,6,7-tetrahydrobenzo[h],7,2]oxazasilonine, (Z)-2,2-dimethyl-3,6-dihydro-2H-benzo[h][1,7,2]dioxasilonine, (Z)-8-isopropoxy-9-methoxy-3,3-dimethyl-1,3,4,7-tetrahydro-benzo[g]-[1,2]oxasilonine and (Z)-2,2,7,7-tetramethyl-2,3,6,7-tetrahydrobenzo[i][1,8,2,7)dioxadisilecine, (C) 2008 Elsevier Ltd, All rights reserved.

  DOI：

  10.1016/j.tetlet.2008.10.067
• 作为产物：
  描述：

  N-(2-羟基-苯基)-4-甲基-苯磺酰胺 、 3-溴丙烯 在 potassium carbonate 作用下， 以 四氢呋喃 、 N,N-二甲基甲酰胺 为溶剂， 反应 24.0h， 以64%的产率得到N-allyl-N-(2-hydroxyphenyl)-4-methylbenzenesulfonamide
  参考文献：
  名称：

  N-烯丙基-2-氨基苯酚的可切换氧化反应：钯催化的烷氧基酰氧基化与分子内 Diels-Alder 反应

  摘要：

  在 PhI(OCOR) 2作为氧化剂的存在下，Pd(II) 催化的N-烯丙基-2-氨基苯酚反应导致烷氧基酰氧基化过程，形成官能化的二氢-1,4-苯并恶嗪。在没有钯催化剂的情况下进行的反应切换到分子内 Diels-Alder 反应 (IMDA) 途径，这是 2-氨基苯酚的氧化脱芳构化、亲核加成和 Diels-Alder 反应级联的结果，突出了氧化剂既是亲核供体又是氧化剂。

  DOI：

  10.1021/acs.orglett.1c02539

文献信息

• INK FOR SCRATCH COLORING AND SHEET WITH INVISIBLE INFORMATION PRINTED
  申请人：Mitsubishi Paper Mills Limited

  公开号：EP2096149A1

  公开（公告）日：2009-09-02

  Disclosed are a scratch color-developable ink comprising an electron-donating colorless or light-color dye precursor, an electron-accepting color developer and a varnish, wherein a solid particle component contained therein has an average particle diameter of 0.3 to 25 µm, a scratch color-developable ink comprising an electron-donating colorless or light-color dye precursor, an electron-accepting color developer and a varnish, wherein an azaphthalide compound is contained as the electron-donating colorless or light-color dye precursor, and an invisible information printed sheet obtained by printing invisible information on a support with the above scratch color-developable ink. The above scratch color-developable ink makes invisible information visible easily by scratching with a finger nail although the color of an invisible information printed portion is hard to develop by frictional contact during usual handling, gives a high developed color intensity and is free from the occurrence of dust during the visualization of invisible information.

  公开了一种由电子捐献型无色或浅色染料前体、电子接受型显色剂和光油组成的划痕显色墨水，其中包含的固体颗粒成分的平均颗粒直径为 0.3至25微米；一种可刮擦显色油墨，由电子捐赠的无色或浅色染料前体、电子接受的显色剂和光油组成，其中含有作为电子捐赠的无色或浅色染料前体的萘化合物；以及一种通过在支撑物上用上述可刮擦显色油墨印刷隐形信息而获得的隐形信息印刷品。 上述划痕显色油墨虽然在通常的操作过程中通过摩擦接触很难使隐形信息印刷部分显色，但用指甲划痕即可轻松显现隐形信息，显色强度高，而且在显现隐形信息时不会产生灰尘。
• SCRATCH COLOR-DEVELOPABLE INK AND INVISIBLE INFORMATION PRINTED SHEET
  申请人：Wakasugi Hisashi

  公开号：US20100021702A1

  公开（公告）日：2010-01-28

  Disclosed are a scratch color-developable ink comprising an electron-donating colorless or light-color dye precursor, an electron-accepting color developer and a varnish, wherein a solid particle component contained therein has an average particle diameter of 0.3 to 25 μm, a scratch color-developable ink comprising an electron-donating colorless or light-color dye precursor, an electron-accepting color developer and a varnish, wherein an azaphthalide compound is contained as the electron-donating colorless or light-color dye precursor, and an invisible information printed sheet obtained by printing invisible information on a support with the above scratch color-developable ink. The above scratch color-developable ink makes invisible information visible easily by scratching with a finger nail although the color of an invisible information printed portion is hard to develop by frictional contact during usual handling, gives a high developed color intensity and is free from the occurrence of dust during the visualization of invisible information.
• US6921740B1
  申请人：——

  公开号：US6921740B1

  公开（公告）日：2005-07-26
• US8283285B2
  申请人：——

  公开号：US8283285B2

  公开（公告）日：2012-10-09
• Switchable Oxidative Reactions of <i>N</i>-allyl-2-Aminophenols: Palladium-Catalyzed Alkoxyacyloxylation vs an Intramolecular Diels–Alder Reaction
  作者：Sabrina Giofrè、Manfred Keller、Leonardo Lo Presti、Egle M. Beccalli、Letizia Molteni

  DOI：10.1021/acs.orglett.1c02539

  日期：2021.10.15

  The Pd(II)-catalyzed reaction of N-allyl-2-aminophenols in the presence of PhI(OCOR)2 as the oxidant resulted in an alkoxyacyloxylation process, with the formation of functionalized dihydro-1,4-benzoxazines. The reaction performed in the absence of palladium catalyst switched to an intramolecular Diels–Alder reaction (IMDA) pathway, which was the result of an oxidative dearomatization of the 2-aminophenol

  在 PhI(OCOR) 2作为氧化剂的存在下，Pd(II) 催化的N-烯丙基-2-氨基苯酚反应导致烷氧基酰氧基化过程，形成官能化的二氢-1,4-苯并恶嗪。在没有钯催化剂的情况下进行的反应切换到分子内 Diels-Alder 反应 (IMDA) 途径，这是 2-氨基苯酚的氧化脱芳构化、亲核加成和 Diels-Alder 反应级联的结果，突出了氧化剂既是亲核供体又是氧化剂。