丁氧基乙氧基乙酸钠 | 67990-17-4

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 中文名称: 丁氧基乙氧基乙酸钠
• 中文别名: 2-(2-丁氧基乙氧基)-乙酸钠盐(1:1)
• 英文名称: Acetic acid, (2-butoxyethoxy)-, sodium salt
• 英文别名: sodium;2-(2-butoxyethoxy)acetate
• CAS: 67990-17-4
• 化学式: C8H15NaO4
• 分子量: 198.19
• InChiKey: JOWTZKYGHSPYKA-UHFFFAOYSA-M

物化性质

• 密度：
  1.32[at 20℃]
• LogP：
  -1.89 at 20℃
• 物理描述：
  Liquid

计算性质

• 辛醇/水分配系数(LogP)：
  -3.43
• 重原子数：
  13
• 可旋转键数：
  7
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.88
• 拓扑面积：
  58.6
• 氢给体数：
  0
• 氢受体数：
  4

文献信息

• Microbubble formation using ultrasound
  申请人：——

  公开号：US20030032879A1

  公开（公告）日：2003-02-13

  Disclosed herein are agents for enhancing the contrast in a diagnostic ultrasound procedure. These agents comprise colloidal dispersions of the liquid-in-liquid type, i.e., emulsions or microemulsions, in which the dispersed liquid phase has a boiling point at or below the body temperature of the organism to be studied and thus undergoes a phase change from a dispersed liquid to a highly echogenic dispersed gaseous foam or kugelschaum following administration to an organism. The liquid state of the dispersed phase allows one to manufacture extremely stable, pharmaceutically acceptable emulsions with particle sizes typically below 1000 nm. The gaseous state at body temperature yields highly echogenic microbubbles, typically below 10,000 nm in diameter, which are effective as ultrasound contrast agents. Intravenous, intraarterial, oral, intraperitoneal, and intrauterine dosage forms, methods of administration, and imaging techniques are described.

  本文公开了一种增强诊断超声成像对比度的药剂。这些药剂包括液体-液体型胶体分散液，即乳液或微乳液，其中分散液相在被检测生物体的体温以下沸点，因此在给生物体注射后从分散液体相转变为高声学对比度的分散气态泡沫或库格尔沙。分散相的液态使得可以制造粒径通常低于1000纳米的极其稳定的药用乳剂。体温下的气态产生高声学对比度的微泡，直径通常低于10,000纳米，有效作为超声对比剂。描述了静脉、动脉内、口服、腹腔内和子宫内剂量形式、给药方法和成像技术。
• Polymerization of silicone microemulsions
  申请人：——

  公开号：US20020091193A1

  公开（公告）日：2002-07-11

  Emulsions and latexes containing polymer particles with a diameter greater than 0.02 micron are prepared by (i) forming a microemulsion containing particles of oligomers with a diameter less than 0.02 micron by combining water, a surfactant, a hydride functional organosilicon oligomer or a mixture of such oligomers, and an alkenyl functional organosilicon oligomer or a mixture of such oligomers; (ii) adding a catalyst to the microemulsion; (iii) initiating polymerization of the oligomers; and (iv) continuing polymerization until an emulsion or latex is formed containing polymer particles with a diameter greater than 0.02 micron.

  制备直径大于0.02微米的聚合物颗粒的乳液和乳胶的方法为：(i)通过将水、表面活性剂、含有氢化功能的有机硅寡聚体或混合物以及烯基功能的有机硅寡聚体或混合物组合形成直径小于0.02微米的寡聚体颗粒的微乳液；(ii)向微乳液中加入催化剂；(iii)启动寡聚体的聚合反应；(iv)继续聚合反应，直到形成直径大于0.02微米的聚合物颗粒的乳液或乳胶。
• Process for removal of sealants from surfaces
  申请人：AMCHEM PRODUCTS, INC.

  公开号：EP0095312A1

  公开（公告）日：1983-11-30

  Processes for removing contaminating sealants used in the automobile and allied industries from water-insoluble surfaces, employing cleaning compositions which are aqueous solutions containing at least one C5-C9 alkanoic acid, normally at a concentration of at least 0.8 g/l and preferably 2.5 - 150 g/l, above all 8 - 60 g/l, as well as optionally other ingredients, notably at least 0.1 g/l and preferably 6 130 g/l of alkali metal phosphate or condensed phosphate. Aqueous compositions for use in the processes may be prepared by dilution of 10% - 25% of aqueous concentrates, usually containing solubility-enhancing agents.

  用于清除汽车和相关工业中用于水不溶性表面的污染性密封剂的工艺，采用的清洗组合物为水溶液，含有至少一种 C5-C9 烷酸，通常浓度至少为 0.8 克/升，最好为 2.5 - 150 克/升，最重要的是 8 - 60 克/升，以及可选的其他成分，特别是至少 0.1 克/升，最好为 6 130 克/升的碱金属磷酸盐或缩合磷酸盐。 工艺中使用的水性组合物可以通过稀释 10%-25%的水性浓缩物来制备，通常含有溶解性增强剂。
• A process for phosphatizing and use thereof
  申请人：HENKEL CORPORATION (a Delaware corp.)

  公开号：EP0151813A2

  公开（公告）日：1985-08-21

  Aqueous compositions containing as essential ingredients; an alkanolamine, an aliphatic carboxylic acid containing 5 to 18 carbon atoms, and an arylenetriazole have been found effective in removing resin-containing sealants from the surfaces of zinc containing metals, such as galvanized steel, without causing changes in the surfaces of the metal, so that phosphate coatings which are subsequently applied to said surfaces are neither streaky nor spotty.

  研究发现，含有烷醇胺、含 5 至 18 个碳原子的脂肪族羧酸和芳烯三唑作为基本成分的水性组合物，能有效去除含锌金属（如镀锌钢）表面上的含树脂密封剂，而不会导致金属表面发生变化，从而使随后涂在所述表面上的磷酸盐涂层既不会出现条纹，也不会有斑点。
• A method of preserving ophthalmic solutions and compositions therefor
  申请人：CIBA-GEIGY AG

  公开号：EP0354186A1

  公开（公告）日：1990-02-07

  A preservative for ophthalmic solutions having an active ingredient is provided, having a hydrogen peroxide content of about 0.001 % to about 0.10 % by weight; and diethylene triamine penta(methylene phosphonic acid), or a physiologically compatible salt thereof, present at about 0.002 % to 0.03 % by weight and/or 0.005 % to about 0.20 % by weight of 1-hydroxyethylidene-1,1-diphosphonic acid, or a physiologically compatible salt thereof.

  提供了一种用于具有活性成分的眼科溶液的防腐剂，其过氧化氢含量约为 0.001 % 至约 0.10 %（按重量计）；二亚乙基三胺五亚甲基膦酸或其生理相容盐的含量约为 0.002 % 至 0.03 %（按重量计）和/或 0.005 % 至约 0.20 %（按重量计），1-羟基亚乙基-1,1-二膦酸或其生理相容盐的含量约为 0.002 % 至 0.03 %（按重量计）和/或 0.005 % 至约 0.20 %（按重量计）。