O⁵,O⁶-diacetyl-O¹,O²-isopropylidene-3'-(2,4,6-trimethyl-phenyl)-4'H-spiro[α-D-3-deoxy-glucofuranose-3,5'-isoxazole] | 39726-25-5

• 分子结构分类: 有机化合物 - 苯类化合物 - 茚满类
• 英文名称: O⁵,O⁶-diacetyl-O¹,O²-isopropylidene-3'-(2,4,6-trimethyl-phenyl)-4'H-spiro[α-D-3-deoxy-glucofuranose-3,5'-isoxazole]
• 英文别名: (R)-1,2-diacetoxy-1-[(6S)-2,2-dimethyl-3'-(2,4,6-trimethyl-phenyl)-(3ac,6rO,6ac)-3a,6a-dihydro-4'H-spiro[furo[2,3-d]dioxole-6,5'-isoxazol]-5c-yl]-ethane
• CAS: 39726-25-5
• 化学式: C₂₄H₃₁NO₈
• 分子量: 461.512
• InChiKey: ARVWUXSHFJVOAF-YVTYUBGGSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.85
• 重原子数：
  33.0
• 可旋转键数：
  5.0
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.62
• 拓扑面积：
  101.88
• 氢给体数：
  0.0
• 氢受体数：
  9.0

反应信息

• 作为产物：
  描述：

  O¹,O²;O⁵,O⁶-diisopropylidene-3'-(2,4,6-trimethyl-phenyl)-4'H-spiro[α-D-3-deoxy-glucofuranose-3,5'-isoxazole] 生成 O⁵,O⁶-diacetyl-O¹,O²-isopropylidene-3'-(2,4,6-trimethyl-phenyl)-4'H-spiro[α-D-3-deoxy-glucofuranose-3,5'-isoxazole]
  参考文献：
  名称：

  D�riv�s C-glycosyliques. IX. Synth�se despiro-?2-isoxazolines et despiro-?1-pyrazolines � partir du d�soxy-3-di-O-isopropylid�ne 1, 2: 5, 6-m�thyl�ne-3-?-D-ribo-hexofurannose. Communication pr�liminaire

  摘要：

  AbstractTreatment of 3‐deoxy‐1, 2:5, 6‐di‐O‐isopropylidène‐3C‐méthylene‐α‐D‐ribo‐hexofuranose with aromatic nitrile oxides led to spiro‐Δ2‐isoxazolines, whereas a Δ1‐pyrazoline was obtained by reacting the same C‐methylenic sugar with diazomethane. Properties of these compounds, a new class of carbohydrates, and 5, 6‐di‐O‐acetyl derivatives thereof are described.

  DOI：

  10.1002/hlca.19720550811