2-[2-(2-thiocyanato-3-phenylpropionyloxy)ethoxy]ethyl acrylate | 447403-72-7

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 2-[2-(2-thiocyanato-3-phenylpropionyloxy)ethoxy]ethyl acrylate
• 英文别名: 1-acryloyloxy-2-[2-(2-thiocyanato-3-phenylpropionyloxy)ethoxy]ethane；2-[2-(2-Thiocyanato-3-phenylpropionyloxy)ethoxy]-ethyl acrylate；2-(2-prop-2-enoyloxyethoxy)ethyl 3-phenyl-2-thiocyanatopropanoate
• CAS: 447403-72-7
• 化学式: C₁₇H₁₉NO₅S
• 分子量: 349.408
• InChiKey: KRAFZAUTKDPTKO-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.2
• 重原子数：
  24
• 可旋转键数：
  13
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.35
• 拓扑面积：
  111
• 氢给体数：
  0
• 氢受体数：
  7

反应信息

• 作为反应物：
  描述：

  potassium thioacyanate 、 4-methylbenzenediazonium tetrafluoroborate 、 2-[2-(2-thiocyanato-3-phenylpropionyloxy)ethoxy]ethyl acrylate 在 copper(II) bis(tetrafluoroborate) 作用下， 以 水 、 丙酮 为溶剂， 生成 2-[2-[3-(4-methylphenyl)-2-thiocyanatopropanoyl]oxyethoxy]ethyl 3-phenyl-2-thiocyanatopropanoate
  参考文献：
  名称：

  摘要：

  The example of diethylene glycol diacrylate was used to demonstrate the possibility of thiocyanatoarylation both by one and by two multiple bonds of compounds with two isolated multiple bonds. The reactions of arenediazonium tetrafluoroborates with diethylene glycol diacrylate in aqueous acetone (1:2) in the presence of catalytic amounts of copper gave 1-acryloyloxy-2-[2-(2-thiocyanato-3-arylpropionyloxy)ethoxy]ethanes. The latter were reacted with arenediazonium tetrafluoroborates in aqueous acetone (1:3) to obtain 1-[2-(2-thiocyanato-3-arylpropionyloxy)ethoxy]-2-(2-thiocyanato-3-arylpropionyloxy)ethanes via thiocyanatoarylation by two multiple bonds.

  DOI：

  10.1023/a:1021677913217
• 作为产物：
  描述：

  硫氰酸铵 、 二丙烯酸二乙二醇酯 、 benzenediazonium tetrafluoroborate 在 copper(II) bis(tetrafluoroborate) 作用下， 以 水 、 丙酮 为溶剂， 反应 2.0h， 以59%的产率得到2-[2-(2-thiocyanato-3-phenylpropionyloxy)ethoxy]ethyl acrylate
  参考文献：
  名称：

  摘要：

  The example of diethylene glycol diacrylate was used to demonstrate the possibility of thiocyanatoarylation both by one and by two multiple bonds of compounds with two isolated multiple bonds. The reactions of arenediazonium tetrafluoroborates with diethylene glycol diacrylate in aqueous acetone (1:2) in the presence of catalytic amounts of copper gave 1-acryloyloxy-2-[2-(2-thiocyanato-3-arylpropionyloxy)ethoxy]ethanes. The latter were reacted with arenediazonium tetrafluoroborates in aqueous acetone (1:3) to obtain 1-[2-(2-thiocyanato-3-arylpropionyloxy)ethoxy]-2-(2-thiocyanato-3-arylpropionyloxy)ethanes via thiocyanatoarylation by two multiple bonds.

  DOI：

  10.1023/a:1021677913217

文献信息

• ——
  作者：B. D. Grishchuk、S. I. Klimnyuk、V. S. Baranovskii、O. V. Boichak、P. M. Gorbovoi

  DOI：10.1023/a:1014046826007

  日期：——