(2S,6R)-4-oxatetracyclo[5.3.2.02,6.08,10]dodec-11-ene-3,5-dione | 944-41-2

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: (2S,6R)-4-oxatetracyclo[5.3.2.02,6.08,10]dodec-11-ene-3,5-dione
• CAS: 944-41-2；7131-63-7；24447-28-7
• 化学式: C₁₁H₁₀O₃
• 分子量: 190.199
• InChiKey: QMLYJZNAGFCCGP-XIDJMXOJSA-N

物化性质

• 沸点：
  364.3±42.0 °C(Predicted)
• 密度：
  1.427±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  0.9
• 重原子数：
  14
• 可旋转键数：
  0
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.64
• 拓扑面积：
  43.4
• 氢给体数：
  0
• 氢受体数：
  3

安全信息

• 危险等级：
  IRRITANT

文献信息

• Compounds, compositions, and methods for treatment and prevention of orthopoxvirus infections and associated diseases
  申请人：Jordan Robert

  公开号：US20080103181A9

  公开（公告）日：2008-05-01

  Methods of using di, tri, and tetracyclic acylhydrazide derivatives and analogs, as well as pharmaceutical compositions containing the same, for the treatment or prophylaxis of viral infections and diseases associated therewith, particularly those viral infections and associated diseases cased by the orthopoxvirus.

  使用二、三、四环腈肟衍生物及类似物的方法，以及含有该物的药物组合物，用于治疗或预防病毒感染及其相关疾病，尤其是由正痘病毒引起的病毒感染和相关疾病。
• Chemicals, compositions, and methods for treatment and prevention of orthopoxvirus infections and associated diseases
  申请人：Jordan F. Robert

  公开号：US20070287735A1

  公开（公告）日：2007-12-13

  Methods of using di, tri, and tetracyclic acylhydrazide derivatives and analogs, as well as pharmaceutical compositions containing the same, for the treatment or prophylaxis of viral infections and diseases associated therewith, particularly those viral infections and associated diseases cased by the orthopoxvirus.

  使用二、三和四环戊二酰肼衍生物及类似物的方法，以及含有它们的药物组合物，用于治疗或预防病毒感染及其相关疾病，特别是由正痘病毒引起的病毒感染和相关疾病。
• 5,6-DIHYDRO-1H-PYRIDIN-2-ONE COMPOUNDS
  申请人：Tran Chinh V.

  公开号：US20100034773A1

  公开（公告）日：2010-02-11

  The invention is directed to 5,6-dihydro-1H-pyridin-2-one compounds and pharmaceutical compositions containing such compounds that are useful in treating infections by hepatitis C virus.

  该发明涉及5,6-二氢-1H-吡啶-2-酮化合物和含有这种化合物的药物组合物，用于治疗丙型肝炎病毒感染。
• Compounds, Compositions and Methods for Treatment and Prevention of Orthopoxvirus Infections and Associated Diseases
  申请人：Jordan Robert

  公开号：US20100227892A1

  公开（公告）日：2010-09-09

  Methods of using di, tri, and tetracyclic acylhydrazide derivatives and analogs, as well as pharmaceutical compositions containing the same, for the treatment or prophylaxis of viral infections and diseases associated therewith, particularly those viral infections and associated diseases caused by the orthopoxvirus.

  使用二、三、四环腈肟衍生物及其类似物的方法，以及含有它们的制药组合物，用于治疗或预防病毒感染及其相关疾病，特别是由正痘病毒引起的病毒感染和相关疾病。
• COMPOUNDS, COMPOSITIONS AND METHODS FOR TREATMENT AND PREVENTION OF ORTHOPOXVIRUS INFECTIONS AND ASSOCIATED DISEASES
  申请人：Jordan Robert

  公开号：US20120020922A1

  公开（公告）日：2012-01-26

  Methods of using di, tri, and tetracyclic acylhydrazide derivatives and analogs, as well as pharmaceutical compositions containing the same, for the treatment or prophylaxis of viral infections and diseases associated therewith, particularly those viral infections and associated diseases caused by the orthopoxvirus.

  使用二、三、四环腈肟衍生物及类似物的方法，以及包含它们的制药组合物，用于治疗或预防病毒感染及其相关疾病，特别是由正痘病毒引起的病毒感染和相关疾病。