N,N-Dimethyl-N'-hexadecanoyl-1,3-propanediaminehydrochloride | 151190-60-2

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: N,N-Dimethyl-N'-hexadecanoyl-1,3-propanediaminehydrochloride
• 英文别名: 3-(Hexadecanoylamino)propyl-dimethylazanium;chloride
• CAS: 151190-60-2
• 化学式: C₂₁H₄₄N₂O*ClH
• 分子量: 377.054
• InChiKey: AYPSJCGISXKEGH-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.96
• 重原子数：
  25
• 可旋转键数：
  18
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.95
• 拓扑面积：
  32.3
• 氢给体数：
  2
• 氢受体数：
  2

文献信息

• Personal care composition
  申请人：Weidmann Holding AG

  公开号：US11278475B2

  公开（公告）日：2022-03-22

  Disclosed are personal care compositions comprising a fibrous material of natural origin and obtained from plants. The fibrous material comprises micro-scaled and/or nano-scaled fibril agglomerates. Such compositions show pleasant skin feel and comfort during and after application, as well as fast drying and fast absorption into skin. The compositions obtained are also particularly well suited for the topical delivery of cosmetic and pharmaceutical active substances into skin. Additionally, a method to obtain said personal care composition is disclosed.

  本发明公开了一种个人护理组合物，该组合物包含一种来自天然植物的纤维材料。这种纤维材料包括微尺度和/或纳米尺度的纤维团块。这种组合物在使用过程中和使用后都会给皮肤带来舒适的感觉，并能快速干燥和被皮肤快速吸收。获得的这种组合物还特别适用于向皮肤局部输送化妆品和药物活性物质。此外，还公开了一种获得所述个人护理组合物的方法。
• PERSONAL CARE COMPOSITION
  申请人：Weidmann Holding AG

  公开号：EP3606500A1

  公开（公告）日：2020-02-12
• HAIR CARE OR HAIR CLEANSING COMPOSITION OR SKIN CARE OR SKIN CLEANSING COMPOSITION
  申请人：Weidmann Holding AG

  公开号：US20220160591A1

  公开（公告）日：2022-05-26

  Disclosed are hair care and hair cleansing compositions as well as skin care and skin cleansing compositions comprising a fibrous material of natural origin and obtained from plants. The fibrous material comprises micro-scaled and/or nano-scaled fibril agglomerates. Such compositions show pleasant skin feel and comfort during and after application, as well as fast drying and fast absorption into skin. The compositions obtained are also particularly well suited for the topical delivery of cosmetic and pharmaceutical active substances into skin. Additionally, a method to obtain said hair care or hair cleansing composition or said skin care or skin cleansing composition is disclosed.
• US5270310A
  申请人：——

  公开号：US5270310A

  公开（公告）日：1993-12-14
• [EN] N-AMINOALKYL AMIDE INHIBITORS OF PROTEIN KINASE C
  申请人：SPHINX PHARMACEUTICALS CORPORATION

  公开号：WO1993011758A1

  公开（公告）日：1993-06-24

  (EN) The invention provides novel compounds having formula (I), wherein R1 is C8 through C15 alkyl; R2 is H, C1 through C10 alkyl, or benzyl; R3 is N-heterocyclic, N-alkylheterocyclic or quaternized N-heterocyclic; and n is 2, 3, 4 or 5. The present invention also provides methods for inhibiting protein kinase C which comprise contacting protein kinase C with an inibitory amount of a compound having formula (I) wherein R1 is C8 through C15 alkyl; R2 is H, C1 through C10 alkyl, or benzyl; R3 is N-heterocyclic, N-alkylheterocyclic, quaternized N-heterocyclic, NR4R5 or N+R4R5R6X-; R4, R5 and R6 are independently C1 through C10 alkyl; n is 2, 3, 4 or 5; and X is an anion.(FR) Nouveaux composés de la formule (I) dans laquelle R1 représente alkyle C8 à C15; R2 représente H, alkyle C1 à C10 ou benzyle; R3 représente N-hétérocyclique, N-alkylhétérocyclique ou N-hétérocyclique quaternisé; et n représente 2, 3, 4 ou 5. La présente invention décrit également des procédés destinés à inhiber la protéine kinase C, qui consistent à mettre en contact de la protéine kinase C avec une quantité inhibitrice d'un composé de la formule (I) dans laquelle R1 représente alkyle C8 à C15; R2 représente H, alkyle C1 à C10 ou benzyle; R3 représente N-hétérocyclique, N-alkylhétérocyclique, N-hétérocyclique quaternisé, NR4R5 ou N+R4R5R6X-, R4, R5 et R6 représentant indépendamment alkyle C1 à C10; n représente 2, 3, 4 ou 5 et X représente un anion.