4-甲基-3-硫烷基戊酸 | 88277-60-5

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 中文名称: 4-甲基-3-硫烷基戊酸
• 英文名称: 3-mercapto-4-methyl-valeric acid
• 英文别名: 3-Mercapto-4-methyl-valeriansaeure；4-Methyl-3-sulfanylpentanoic acid
• CAS: 88277-60-5
• 化学式: C₆H₁₂O₂S
• mdl: MFCD19229395
• 分子量: 148.226
• InChiKey: HINDHEBMAYXQCL-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.4
• 重原子数：
  9
• 可旋转键数：
  3
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.833
• 拓扑面积：
  38.3
• 氢给体数：
  2
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  4-甲基-3-戊烯酸 在 alkaline solution 作用下， 生成 4-甲基-3-硫烷基戊酸
  参考文献：
  名称：

  THE KINETICS OF BASIC HYDROLYSIS OF SOME γ-LACTONES AND γ-THIOLACTONES IN AQUEOUS ACETONE¹

  摘要：

  DOI：

  10.1021/jo01377a017

文献信息

• CURABLE COMPOSITION CONTAINING HYDROXYTHIOL COMPOUND, AND CURED PRODUCTS THEREOF
  申请人：MUROFUSHI Katsumi

  公开号：US20100047713A1

  公开（公告）日：2010-02-25

  Curable compositions have high sensitivity and excellent developability, and further have good storage properties as required. The compositions include a hydroxythiol compound represented by Formula (1) below and a compound with an ethylenically unsaturated double bond: wherein R 1 and R 2 are each independently a hydrogen atom, a C1-10 alkyl group or an aromatic ring; X is an aliphatic group, an aromatic ring-containing group or a heterocyclic ring-containing group; Y is an ester bond; k and l are each an integer ranging from 1 to 20; m is an integer of 0, 1 or 2; and n is 0 or 1.

  可治疗组合物具有高灵敏度和优异的显影性能，并且具有所需的良好储存性能。该组合物包括以下式(1)所表示的羟基硫醇化合物和具有乙烯不饱和双键的化合物：其中，R1和R2各自独立地表示氢原子、C1-10烷基或芳香环；X表示脂肪族基、含芳香环的基团或含杂环的基团；Y表示酯键；k和l各自为1至20之间的整数；m为0、1或2的整数；n为0或1。
• DUAL-ACTING ANTIHYPERTENSIVE AGENTS
  申请人：Allegretti Paul

  公开号：US20120264752A1

  公开（公告）日：2012-10-18

  The invention is directed to compounds having the formula: wherein: Ar, r, Y, Z, Q, W, X, and R 5-7 are as defined in the specification, and pharmaceutically acceptable salts thereof. These compounds have AT 1 receptor antagonist activity and neprilysin inhibition activity. The invention is also directed to pharmaceutical compositions comprising such compounds; methods of using such compounds; and process and intermediates for preparing such compounds.

  本发明涉及具有以下公式的化合物：其中：Ar、r、Y、Z、Q、W、X和R5-7如规范中所定义，并且其药学上可接受的盐。这些化合物具有AT1受体拮抗活性和神经肽酶抑制活性。本发明还涉及包含这些化合物的制药组合物；使用这些化合物的方法；以及制备这些化合物的过程和中间体。
• PHOTO-CURING MATERIAL MANUFACTURING METHOD, AND PHOTO-CURING MATERIAL AND ARTICLE
  申请人：Asahi Glass Company Limited

  公开号：EP2360195A1

  公开（公告）日：2011-08-24

  To provide a photocurable material which can form a cured product having a high transparency and a high refractive index, a process for producing the material easily, and an article having a high transparency and a high refractive index. The photocurable material is obtained by a production process comprising (i) a step of reacting a polymerizable component (A) comprised of at least one type of a compound (a) having a (meth)acryloyloxy group, and a compound (B) having a mercapto group and a carboxy group to obtain a surface modifier (C) which has the carboxy group derived from the compound (B) at a terminal, (ii) a step of modifying the surface of inorganic fine particles (D) with the surface modifier (C) to obtain surface-modified inorganic fine particles (E), and (iii) a step of obtaining a photocurable material which contains the surface-modified inorganic fine particles (E), a polymerizable component (F) comprised of at least one type of a compound (f) having a (meth)acryloyloxy group, and a photopolymerization initiator (G).

  提供一种可形成具有高透明度和高折射率的固化物的光固化材料、一种易于生产该材料的工艺以及一种具有高透明度和高折射率的制品。 这种光固化材料是通过以下生产工艺获得的： (i) 第一步：使由至少一种具有(甲基)丙烯酰氧基的化合物(a)和具有巯基和羧基的化合物(B)组成的可聚合组分(A)与表面改性剂(C)反应，表面改性剂(C)的末端具有来自化合物(B)的羧基、(ii) 用表面改性剂（C）改性无机微粒（D）的表面，以获得表面改性无机微粒 （E），以及 (iii) 获得光固化材料的步骤，该材料包含表面改性无机微粒（E）、由至少一种具有 （甲基）丙烯酰氧基的化合物（f）和光聚合引发剂（G）组成的可聚合组分（F）。
• ACTINIC-RAY-CURABLE COMPOSITION AND CURED OBJECT OBTAINED THEREFROM
  申请人：Showa Denko K.K.

  公开号：EP3428198A1

  公开（公告）日：2019-01-16

  There is provided an active energy ray-curable composition having excellent storage stability. The active energy ray-curable composition includes: an active energy ray-curable compound (A) having an unsaturated ethylenic double bond; a thiol compound (B) having two or more mercapto groups in one molecule; a reaction inhibitor (C) configured to inhibit a reaction between the unsaturated ethylenic double bond and the mercapto groups; a radical polymerization inhibitor (D) ; and water (E), in which the content of the water (E) is 0.05 ppm by mass or more and less than 1% by mass. The content of the reaction inhibitor (C) is 0.005 parts by mass or more and 10 parts by mass or less when the total content of the active energy ray-curable compound (A) and the thiol compound (B) is 100 parts by mass. The content of the radical polymerization inhibitor (D) is 0.005 parts by mass or more and 5 parts by mass or less when the total content of the active energy ray-curable compound (A) and the thiol compound (B) is 100 parts by mass.

  本发明提供了一种具有优异储存稳定性的活性能量射线固化组合物。该活性能量射线固化组合物包括：具有不饱和乙烯双键的活性能量射线固化化合物 (A)；在一个分子中具有两个或两个以上巯基的硫醇化合物 (B)；用于抑制不饱和乙烯双键与巯基之间反应的反应抑制剂 (C)；自由基聚合抑制剂 (D) ；以及水 (E)，其中水 (E) 的含量为 0.05 ppm 或更多，小于 1%（质量分数）。当活性能量射线固化化合物（A）和硫醇化合物（B）的总含量为 100 份时，反应抑制剂 （C）的含量为 0.005 份（以质量为单位）或以上，10 份（以质量为单位）或以下。当活性能量射线固化化合物 (A) 和硫醇化合物 (B) 的总含量为 100 份时，自由基聚合抑制剂 (D) 的含量为 0.005 份或更多，5 份或更少。
• RESIN COMPOSITION FOR ACOUSTIC MATCHING LAYER, CURED PRODUCT, ACOUSTIC MATCHING SHEET, ACOUSTIC WAVE PROBE, ACOUSTIC WAVE MEASUREMENT DEVICE, PRODUCTION METHOD FOR ACOUSTIC WAVE PROBE, AND MATERIAL SET FOR ACOUSTIC MATCHING LAYER
  申请人：FUJIFILM Corporation

  公开号：EP3706438A1

  公开（公告）日：2020-09-09

  Provided is a resin composition for an acoustic matching layer, the resin composition including metal particles (A), an epoxy resin (B), a polythiol compound (C), and a cure-accelerating compound (D). The epoxy resin (B) includes at least one epoxy resin selected from the group consisting of bisphenol A epoxy resins, bisphenol F epoxy resins, and phenol novolac epoxy resins, and the polythiol compound (C) includes a compound having at least two specific partial structures. Also provided are a cured product formed of the composition, an acoustic matching sheet, an acoustic probe, an acoustic measuring apparatus, and a method for producing an acoustic probe. Further provided is an acoustic matching layer material set suitable for preparation of the composition.

  本发明提供了一种用于声学匹配层的树脂组合物，该树脂组合物包括金属颗粒（A）、环氧树脂（B）、聚硫醇化合物（C）和固化加速化合物（D）。环氧树脂（B）包括从双酚 A 环氧树脂、双酚 F 环氧树脂和苯酚酚醛环氧树脂组成的组中选出的至少一种环氧树脂，而聚硫醇化合物（C）包括具有至少两种特定部分结构的化合物。此外，还提供了由该组合物形成的固化产品、声学匹配片材、声学探头、声学测量设备以及生产声学探头的方法。此外，还提供了一套适用于制备该组合物的声学匹配层材料。