H-Lys-Gly-OH | 7563-03-3

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: H-Lys-Gly-OH
• 英文别名: Lys-Gly；lysyl-glycine；2-(2,6-diaminohexanoylamino)acetic acid
• CAS: 7563-03-3
• 化学式: C₈H₁₇N₃O₃
• 分子量: 203.241
• InChiKey: HGNRJCINZYHNOU-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -3.9
• 重原子数：
  14
• 可旋转键数：
  7
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.75
• 拓扑面积：
  118
• 氢给体数：
  4
• 氢受体数：
  5

文献信息

• Modified labeled nucleotides and polynucleotides and methods of preparing, utilizing and detecting same
  申请人：ENZO BIOCHEM, INC.

  公开号：EP0285057A2

  公开（公告）日：1988-10-05

  Nucleotides and polynucleotides, including DNA, are chemically modified or labeled so as to be capable of ready detection when attached to and/or incorporated in nucleic acid material.

  核苷酸和多核苷酸（包括 DNA）经过化学修饰或标记，当附着在核酸材料上和/或掺入核酸材料中时，可随时进行检测。
• Protein with a moiety capable of chelating ions attached thereto
  申请人：ENZO BIOCHEM, INC.

  公开号：EP0618228A1

  公开（公告）日：1994-10-05

  Disclosed is a protein to which a moiety capable of chelating an ion is directly or indirectly attached, said attachment being characterized in not interfering substantially with the ability of the moiety to chelate ions.

  本发明公开了一种蛋白质，其上直接或间接附着有能够螯合离子的分子，所述附着物的特点是不会严重干扰分子螯合离子的能力。
• METHOD OF STRENGTHENIG THE TASTE OF SODIUM CHLORIDE, AGENT FOR STRENGTHENING THE TASTE OF SODIUM CHLORIDE, SODIUM CHLORIDE-TASTE SEASONING AND FOOD HAVING STRENGTHENED TASTE OF SODIUM CHLORIDE
  申请人：KYOWA HAKKO KOGYO CO., LTD.

  公开号：EP1163853A1

  公开（公告）日：2001-12-19

  The present invention relates to a method of enhancing the salty taste of a food or beverage containing salt which comprises adding an acidic peptide or a peptide obtained by subjecting a protein to hydrolysis and deamidation to the food or beverage, a salty taste enhancer comprising the peptide as an active ingredient, a salty taste seasoning agent comprising the peptide and salt, and a food or beverage comprising the salty taste enhancer or the salty taste seasoning agent.

  本发明涉及一种增强含盐食品或饮料咸味的方法，该方法包括在食品或饮料中添加酸性肽或通过对蛋白质进行水解和脱氨基处理而获得的肽、包含该肽作为活性成分的咸味增强剂、包含该肽和盐的咸味调味剂，以及包含咸味增强剂或咸味调味剂的食品或饮料。
• NOVEL POLYPEPTIDES AND ANTI-HIV DRUGS CONTAINING THE SAME
  申请人：Seikagaku Corporation

  公开号：EP1323730A1

  公开（公告）日：2003-07-02

  The present invention relates to a polypeptide represented by the formula:         A1-Arg-A2-Cys-Tyr-A3-A4-X-A5-A6-Cit-Cys-A7     (I) (wherein A1 represents a hydrogen atom or an arginine, lysine, ornithine, citrulline, alanine residue, etc.; A2 represents an aromatic amino acid residue; A3, A4 and A6 represent an arginine, lysine, ornithine, citrulline or alanine residue, A5 represents a tyrosine, phenylalanine, alanine, naphthylalanine or citrulline residue; A7 represents a lysine or arginine residue in which a carboxyl group may be amidated; X represents a D-ornithyl-proline, prolyl-D-ornithine, D-lysyl-proline residue, etc.; provided that either of A1, A3, A4, A5, A6 and A7 is an alanine residue, etc., or X is citrulline, etc.) or a salt thereof.

  本发明涉及一种由式表示的多肽： A1-Arg-A2-Cys-Tyr-A3-A4-X-A5-A6-Cit-Cys-A7 (I) (其中 A1 代表一个氢原子或一个精氨酸、赖氨酸、鸟氨酸、瓜氨酸、丙氨酸残基等；A2 代表一个芳香族氨基酸。A2 代表芳香族氨基酸残基；A3、A4 和 A6 代表精氨酸、赖氨酸、鸟氨酸、瓜氨酸或丙氨酸残基，A5 代表酪氨酸、苯丙氨酸、丙氨酸、萘丙氨酸或瓜氨酸残基；A7 代表赖氨酸或精氨酸残基，其中的羧基可能被酰胺化；X 代表 D-鸟氨酰-脯氨酸、脯氨酰-D-鸟氨酸、D-赖氨酰-脯氨酸残基等。条件是 A1、A3、A4、A5、A6 和 A7 中的任一个是丙氨酸残基等、或 X 是瓜氨酸等）或其盐。
• 4F-benzoyl-TN14003 combined with rituximab for use in the treatment of a tumour
  申请人：Biokine Therapeutics LTD.

  公开号：EP2759302A2

  公开（公告）日：2014-07-30

  The present invention is directed to novel therapeutic uses of T-140 analog peptides and compositions comprising same. Specifically, the invention provides compositions and methods useful in cancer therapy.

  本发明涉及 T-140 类似肽的新型治疗用途以及包含 T-140 类似肽的组合物。具体而言，本发明提供了用于癌症治疗的组合物和方法。