2-Amino-5-methoxy-4-methyl-benzaldehyd | 70128-05-1

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯酚醚
• 英文名称: 2-Amino-5-methoxy-4-methyl-benzaldehyd
• 英文别名: 2-Amino-5-methoxy-4-methylbenzaldehyde
• CAS: 70128-05-1
• 化学式: C₉H₁₁NO₂
• 分子量: 165.192
• InChiKey: ONPGEALQUUTDDU-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.6
• 重原子数：
  12
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.22
• 拓扑面积：
  52.3
• 氢给体数：
  1
• 氢受体数：
  3

文献信息

• [EN] COMBINATION ANTI-CANCER PRODUCTS AND METHODS<br/>[FR] PRODUITS ANTI-CANCÉREUX COMBINÉS ET PROCÉDÉS
  申请人：[en]ANKH LIFE SCIENCES LIMITED

  公开号：WO2022011132A1

  公开（公告）日：2022-01-13

  Combination dosage forms of anti-cancer products include components a) and b), where component a) comprises individual amounts of curcumin, harmine, isovanillin, and component b) comprises an agent selected from the group consisting of EGFR inhibitors, CDK 4/6 inhibitors, 5-fluorouracil, checkpoint inhibitors, anti-metabolites, prodrugs thereof, and mixtures thereof. The products may be administered to mammalian subjects suffering from a variety of cancers, to provide a synergistic therapeutic effect.
• [EN] INHIBITION OF COVID-19 VIRUS BY MULTIPLE-COMPONENT FORMULATIONS<br/>[FR] INHIBITION DU VIRUS DE LA COVID-19 PAR DES FORMULATIONS À COMPOSANTS MULTIPLES
  申请人：[en]ANKH LIFE SCIENCES LIMITED

  公开号：WO2022140561A1

  公开（公告）日：2022-06-30

  The treatment of human subjects exposed to, or potentially exposed to SARS-CoV-2 virus, or suffering from COVID-19, comprises the step of administering to the human subjects a multiple-component antiviral formulation comprising a curcumin component, harmine component, and isovanillin component, and/or variants thereof. The formulation may also be used to inhibit SARS-CoV-2 virus in cell-based assays or in the manufacture of antiviral medicaments.
• [EN] LIPID CRYSTALLINE COMPOSITIONS WITH ENHANCED STABILITY FOR TOPICAL DELIVERY OF ACTIVE AGENT COMBINATIONS<br/>[FR] COMPOSITIONS CRISTALLINES LIPIDIQUES À STABILITÉ AMÉLIORÉE POUR ADMINISTRATION TOPIQUE DE COMBINAISONS D'AGENTS ACTIFS
  申请人：[en]ANKH LIFE SCIENCES LIMITED

  公开号：WO2022261466A1

  公开（公告）日：2022-12-15

  Multiple active component therapeutic formulations are described comprising at least two active agents selected from the group consisting of an isovanillin component, a harmine component, and a curcumin component, stabilized in a self-supporting lipid crystalline formulation for topical application. The formulation maintains the active agents in a stable form during storage and will melt at body temperature when applied to the skin, wherein the lipid crystals melt into a liquid crystalline structure thereby releasing the active agents to the applied area of the skin or tissue to render their therapeutic effect.