3-O-phenylglycerylascorbic acid | 1120360-57-7

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯酚醚
• 英文名称: 3-O-phenylglycerylascorbic acid
• 英文别名: (2R)-2-[(1S)-1,2-dihydroxyethyl]-4-hydroxy-3-(2-hydroxy-3-phenoxypropoxy)-2H-furan-5-one
• CAS: 1120360-57-7
• 化学式: C₁₅H₁₈O₈
• 分子量: 326.303
• InChiKey: YYPRLRMEGZSOFL-DALSCRRLSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -0.5
• 重原子数：
  23
• 可旋转键数：
  8
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.4
• 拓扑面积：
  126
• 氢给体数：
  4
• 氢受体数：
  8

文献信息

• ASCORBIC ACID DERIVATIVE OR SALT THEREOF, PRODUCTION METHOD THEREOF, AND COSMETIC
  申请人：Yoshioka Masato

  公开号：US20110059034A1

  公开（公告）日：2011-03-10

  Disclosed is an ascorbic acid derivative or a salt thereof wherein at least one of hydrogen atoms in hydroxy groups at the 2-position and the 3-position of ascorbic acid is substituted by R—O—CH 2 —CH(OH)—CH 2 —, R—O—CH 2 —CH(CH 2 OH)—, R—CH(CH 2 OH)—, R—CH(OH)—CH 2 — (wherein R represents an alkyl group, an alkenyl group or a phenyl group), or a hydroxycyclohexyl group. Also disclosed is a method for producing an ascorbic acid derivative or a salt thereof, which is characterized by reacting ascorbic acid with an epoxy compound such as an alkyl glycidyl ether, an epoxy alkane or an alicyclic epoxy.

  本发明涉及一种抗坏血酸衍生物或其盐，其中抗坏血酸的2-位和3-位羟基中的至少一个氢原子被R-O-CH2-CH（OH）- -，R-O- -CH（ OH）-，R-CH（ OH）-，R-CH（OH）- -（其中R代表烷基，烯基或苯基）或羟基环己基取代。本发明还公开了一种制备抗坏血酸衍生物或其盐的方法，其特征在于将抗坏血酸与环氧化合物（例如烷基环氧乙醚，环氧烷或脂环烷环氧）反应。
• ASCORBIC ACID DERIVATIVE OR SALT THEREOF, METHOD FOR PRODUCING THE SAME, AND COSMETIC PREPARATION
  申请人：Seiwa Kasei Company, Limited

  公开号：EP2189452A1

  公开（公告）日：2010-05-26

  Disclosed is an ascorbic acid derivative or a salt thereof wherein at least one of hydrogen atoms in hydroxy groups at the 2-position and the 3-position of ascorbic acid is substituted by R-O-CH2-CH(OH)-CH2-, R-O-CH2-CH(CH2OH)-, R-CH(CH2OH)-, R-CH(OH)-CH2- (wherein R represents an alkyl group, an alkenyl group or a phenyl group), or a hydroxycyclohexyl group. Also disclosed is a method for producing an ascorbic acid derivative or a salt thereof, which is characterized by reacting ascorbic acid with an epoxy compound such as an alkyl glycidyl ether, an epoxy alkane or an alicyclic epoxy.

  公开了一种抗坏血酸衍生物或其盐，其中抗坏血酸2位和3位羟基中的至少一个氢原子被R-O-CH2-CH(OH)- -、R-O- -CH( OH)-、R-CH( OH)-、R-CH(OH)- -（其中R代表烷基、烯基或苯基）或羟基环己基取代。还公开了一种生产抗坏血酸衍生物或其盐的方法，其特点是将抗坏血酸与环氧化合物如烷基缩水甘油醚、环氧烷或脂环族环氧化合物反应。
• ASCORBIC ACID DERIVATIVES AND SALTS THEREOF, PROCESS FOR THEIR PRODUCTION, AND COSMETIC PREPARATIONS THEREOF
  申请人：Seiwa Kasei Company, Limited

  公开号：EP2189452B1

  公开（公告）日：2012-11-21
• US8163939B2
  申请人：——

  公开号：US8163939B2

  公开（公告）日：2012-04-24