Acetylpenicillin | 876026-16-3

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: Acetylpenicillin
• 英文别名: Methylpenicillin；DL-α-6-Acetamino-penicillansaeure；6β-acetylamino-penicillanic acid；6-Acetamido-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
• CAS: 876026-16-3
• 化学式: C₁₀H₁₄N₂O₄S
• 分子量: 258.298
• InChiKey: FKKLEFAXOOUTAS-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.5
• 重原子数：
  17
• 可旋转键数：
  2
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.7
• 拓扑面积：
  112
• 氢给体数：
  2
• 氢受体数：
  5

文献信息

• [EN] Kit and Methods for the Rapid Detection of the Absence or Presence of a beta-Lactamase in Samples of Body Fluids<br/>[FR] KIT ET MÉTHODE DE DÉTECTION RAPIDE DE L'ABSENCE OU DE LA PRÉSENCE D'UNE BÊTA-LACTAMASE DANS DES ÉCHANTILLONS DE LIQUIDES CORPORELS
  申请人：UNIV DE FRIBOURG

  公开号：WO2017060427A1

  公开（公告）日：2017-04-13

  The present invention concerns a kit and methods for the detection of absence or presence of a β-lactamase, for examplea penicillinase, in a sample comprising or derived from a body fluid taken from a patient suffering from aninfection. In some embodiments, the goal of the invention is to rapidly identify infections which can be treated effectively with apenicillin compound. The invention contributes to slowing down the occurrence of resistances to last generation antibiotics. This is achieved by using penicillin compounds for treating infections whenever this can be done efficiently.In brief, the present invention provides a tool for maximizing the use and efficiency of penicillinantibiotics.In other embodiments, the test kit of the invention can be used to detect cephalosporinases(including ESBLs)or carbapenemases.