N-(1-Carbamoyl-ethyl)-2-methyl-acrylamide | 24214-01-5

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: N-(1-Carbamoyl-ethyl)-2-methyl-acrylamide
• 英文别名: N-(1-amino-1-oxopropan-2-yl)-2-methylprop-2-enamide
• CAS: 24214-01-5
• 化学式: C₇H₁₂N₂O₂
• 分子量: 156.184
• InChiKey: WTHGIRNPBGZUQZ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -0.6
• 重原子数：
  11
• 可旋转键数：
  3
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.43
• 拓扑面积：
  72.2
• 氢给体数：
  2
• 氢受体数：
  2

文献信息

• AMINO ACID MIMETIC COPOLYMERS AND MEDICAL DEVICES COATED WITH THE COPOLYMERS
  申请人：Pacetti Stephen

  公开号：US20080125514A1

  公开（公告）日：2008-05-29

  Biocompatible polymers are manufactured to include an amino acid mimetic monomer and one or more hydrophobic acrylate monomers. The amino acid mimetic monomers are selected to mimic the side chain of the amino acids asparagine or glutamine. The amino acid mimetic monomer can be a methacryloyl or acryloyl derivative of 2-hydroxyacetamide, 3-hydroxypropionamide, alaninamide, lactamide, or glycinamide. These amide functional groups offer the advantage of moderate hydrophilicity with little chemical reactivity. The amino acid mimetic monomer can be copolymerized with one or more hydrophobic acrylate monomers to obtain desired coating properties.
• METHODS FOR MANUFACTURING AMINO ACID MIMETIC COPOLYMERS AND USE OF SAME
  申请人：Pacetti Stephen

  公开号：US20080124450A1

  公开（公告）日：2008-05-29

  Biocompatible polymers are manufactured to include an amino acid mimetic monomer and one or more hydrophobic acrylate monomers. The amino acid mimetic monomers are selected to mimic the side chain of the amino acids asparagine or glutamine. The amino acid mimetic monomer can be a methacryloyl or acryloyl derivative of 2-hydroxyacetamide, 3-hydroxypropionamide, alaninamide, lactamide, or glycinamide. These amide functional groups offer the advantage of moderate hydrophilicity with little chemical reactivity. The amino acid mimetic monomer can be copolymerized with one or more hydrophobic acrylate monomers to obtain desired coating properties.
• PROSTACYCLIN COMPOSITIONS FOR REGULATION OF FRACTURE REPAIR AND BONE FORMATION
  申请人：MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH

  公开号：US20150164853A1

  公开（公告）日：2015-06-18

  The present disclosure provides a prostacyclin coated implant to enhance fracture repair and bone formation comprising: an implant; and a prostacyclin coating comprising a prostacyclin compound disposed in a polymer coating the implant, wherein the prostacyclin coating releases the prostacyclin compound which enhances fracture repair and bone formation.
• US7622537B2
  申请人：——

  公开号：US7622537B2

  公开（公告）日：2009-11-24
• US7928177B2
  申请人：——

  公开号：US7928177B2

  公开（公告）日：2011-04-19