[Pt(diethylenetriamine)I](1+) | 22418-33-3

• 分子结构分类: 有机化合物
• 英文名称: [Pt(diethylenetriamine)I](1+)
• 英文别名: N'-(2-aminoethyl)ethane-1,2-diamine;iodoplatinum(1+)
• CAS: 22418-33-3
• 化学式: C₄H₁₃IN₃Pt
• 分子量: 425.152
• InChiKey: NNEQCONUZCQITA-UHFFFAOYSA-M

计算性质

• 辛醇/水分配系数(LogP)：
  -4.51
• 重原子数：
  9.0
• 可旋转键数：
  4.0
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  64.07
• 氢给体数：
  3.0
• 氢受体数：
  3.0

反应信息

• 作为反应物：
  描述：

  1-甲基尿嘧啶 、 [Pt(diethylenetriamine)I](1+) 在 AgNO₃ 、 NaOH 作用下， 以 水 为溶剂， 以74%的产率得到[dienPt(1-methyluracilate-N3)]NO3 * H2O
  参考文献：
  名称：

  The Uracil C(5) Position as a Metal Binding Site:  Solution and X-ray Crystal Structure Studies of Pt^II and Hg^II Compounds

  摘要：

  1,3-Dimethyluracil (1,3-DimeU) reacts with trans-[(CH3NH2)(2)Pt(H2O)(2)](+) to give trans-[(CH3NH2)(2)Pt(1,3-DimeU-C-5)(H2O)]X (X = NO3-, 1a, ClO4-, 1b) and subsequently with NaCl to give trans-(CH3NH2)(2)Pt(1,3-DimeU-C5)Cl (2) or with NH3 to yield trans-[(CH3NH2)(2)Pt(1,3-DimeU-C5)(NH3)]Cl (3). In a similar way, (dien)Pt-II forms [dienPt(1,3-DimeU-C5)](+) (4). Reactions leading to formation of 1 and 4 are slow, taking days. In contrast, Hg(CH3COO)(2) reacts fast with 1,3-DimeU to give (1,3-DimeU-C5)Hg(CH3COO) (5). Both 1-methyluracil(1-lMeUH) and uridine (urdH) react with (dien)Pt-II initially at N(3) and subsequently with either (dien)Pt-II or Hg(CH3COO)(2) also at C(5) to give the diplatinated species 7 and 9 or the mixed PtHg complex 8. C(5) binding of either Pt-II or Hg-II is evident from coupling of uracil-H(6) with either Pt-195 or Hg-199 nuclei and (3)J values of 47-74 Hz (for Pt compounds) and 185-197 Hz (for Hg compounds). J values of Pt compounds are influenced both by the ligands trans to the uracil C(5) position and by the number of metal entities bound to a uracil ring. Both 2 and 5 were X-ray structurally characterized. 2: monoclinic system, space group P2(1)/c, a (6) Angstrom, c = 25.655 (10) Angstrom, beta = 145.55(3)degrees, V = 2621.9(28) Angstrom(3), Z = 4. 5: monoclinic system, space group P2(1)/c, a = 4.905(2) Angstrom, b = 18.451(6) Angstrom, c = 11.801(5) Angstrom, beta = 94.47(3)degrees, V = 1064.77(72) Angstrom(3), Z = 4.

  DOI：

  10.1021/ic950842c
• 作为产物：
  描述：

  Pt⁽²⁺⁾*NH₂CH₂CH₂NCH₂CH₂NH₂^(1-)*(CH₃)2SO = [Pt(NH₂CH₂CH₂NCH₂CH₂NH₂)((CH₃)2SO)]⁽¹⁺⁾ 在 NaI 作用下， 以 sodium hydroxide 为溶剂， 生成 [Pt(diethylenetriamine)I](1+)
  参考文献：
  名称：

  Romeo, Raffaello; Minniti, Domenico; Alibrandi, Giuseppe, Inorganic Chemistry, 1986, vol. 25, # 12, p. 1944 - 1947

  摘要：

  DOI：

文献信息

• Electronic Tuning of the Lability of Pt(II) Complexes through π-Acceptor Effects. Correlations between Thermodynamic, Kinetic, and Theoretical Parameters
  作者：Andreas Hofmann、Deogratius Jaganyi、Orde Q. Munro、Günter Liehr、Rudi van Eldik

  DOI：10.1021/ic020605r

  日期：2003.3.1

  lability of [Pt(terpy)L]((2)(-)(n)+) (terpy = 2,2':6',2' '-terpyridine) complexes. To gain further insight into this phenomenon, the pi-acceptor effect was varied systematically by studying the lability of [Pt(diethylenetriamine)OH(2)](2+) (aaa), [Pt(2,6-bis-aminomethylpyridine)OH(2)](2+) (apa), [Pt(N-(pyridyl-2-methyl)-1,2-diamino-ethane)OH(2)](2+) (aap), [Pt(bis(2-pyridylmethyl)amine)OH(2)](2+) (pap)

  pi受体效应通常用于解释[Pt（terpy）L]（（2）（-）（n）+）异常高的不稳定性（terpy = 2,2'：6'，2''-terpyridine ）复合体。为了进一步了解这种现象，通过研究[Pt（二亚乙基三胺）OH（2）]（2+）（aaa），[Pt（2,6-双-氨基甲基吡啶）的不稳定性，系统地改变了pi受体的作用。 OH（2）]（2+）（apa），[Pt（N-（吡啶-2-甲基）-1,2-二氨基乙烷）OH（2）]（2+）（aap），[Pt（双（2-吡啶基甲基）胺）OH（2）]（2+）（pap），[Pt（2,2'-联吡啶）（NH（3））（OH（2））]（2+）（app ）和[Pt（terpy）OH（2）]（2+）（ppp）。确定了apa前体[Pt（2,6-双-氨基甲基吡啶）Cl] Cl.H（2）O的晶体结构。水被一系列亲核试剂取代，即。硫脲，N，N-二甲基硫脲，N，N，N'，N'-四甲
• Substitution Reactions of Platinum(II)−Nucleobase Complexes by Associative Mechanism Involving Pseudorotation of the Five-Coordinate Intermediate
  作者：Marjaana Mikola、Karel D. Klika、Anu Hakala、Jorma Arpalahti

  DOI：10.1021/ic9810945

  日期：1999.2.1

  both nucleophiles (Y), the observed rate constant linearly increases with increasing [Y] up to 1000-fold excess of Y. Plots of k(1,obs) vs [Y] were employed to calculate the rate parameters k(S) for the solvent path and k(Y) for the nucleophile-dependent path by the equation k(1,obs) = k(S) + k(Y)[Y] at different temperatures. The following activation parameters were obtained at 298.2 K for the reaction

  N7电镀的鸟苷和腺苷络合物的取代反应[Pt（dien）（Guo-N7）]（2+）（1），[Pt（dien）（Ado-N7）]（2+）（2），二烯硫脲（tu）和I（-）在不同温度下在pH范围为1.4-8.3的水溶液中进行了研究。两种配合物与I（-）的反应在整个研究的pH范围内均遵循通常的缔合双路径机理，在中性条件下（pH 6.5）与硫脲的反应也是如此。对于两个亲核试剂（Y），观察到的速率常数都随[Y]的增加而线性增加，最高可达Y的1000倍。k（1，obs）与[Y]的关系图用于计算速率参数k（S）在不同的温度下，通过方程式k（1，obs）= k（S）+ k（Y）[Y]可以确定溶剂路径和亲核试剂依赖路径的k（Y）。在298获得以下激活参数。2 K用于硫脲与1，DeltaH（）=（72 +/- 1）kJ mol（-）（1）和DeltaS（）=（-79 +/- 4）JK（-）（1）mol的反应（
• Pitteri, Bruno; Marangoni, Giampaolo; Cattalini, Lucio, Journal of the Chemical Society, Dalton Transactions, 1995, p. 3853 - 3860
  作者：Pitteri, Bruno、Marangoni, Giampaolo、Cattalini, Lucio、Bobbo, Tatiana

  DOI：——

  日期：——
• Kinetics of the anation of aquadiethylenetriamineplatinum(II) ions
  作者：Mirjana Kotowski、Donald A. Palmer、Hartwig Kelm

  DOI：10.1016/s0020-1693(00)90972-1

  日期：1980.1
• Effect of pressure on the substitution reactions of [Pt(dien)X]+ complexes in aqueous solution
  作者：D.A. Palmer、H. Kelm

  DOI：10.1016/s0020-1693(00)91083-1

  日期：1976.1