2-chloro-3-[(2,6-diisopropyl-phenylimino)methyl]phenol | 1293409-74-1

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 2-chloro-3-[(2,6-diisopropyl-phenylimino)methyl]phenol
• 英文别名: 2-Chloro-3-[[2,6-di(propan-2-yl)phenyl]iminomethyl]phenol
• CAS: 1293409-74-1
• 化学式: C₁₉H₂₂ClNO
• 分子量: 315.843
• InChiKey: QJIMJEVFVUIXFN-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.7
• 重原子数：
  22
• 可旋转键数：
  4
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.32
• 拓扑面积：
  32.6
• 氢给体数：
  1
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  bis(1,5-cyclooctadiene)nickel (0) 、 氯二异丙基膦 、 2-chloro-3-[(2,6-diisopropyl-phenylimino)methyl]phenol 在 4-N,N-dimethylaminopyridine 作用下， 以 四氢呋喃 为溶剂， 以84%的产率得到
  参考文献：
  名称：

  Synthesis, characterization and application of pincer-type nickel iminophosphinite complexes

  摘要：

  Two pincer-type nickel iminophosphinite complexes, [(2-(CH=NR)-6-(OPR'(2))C(6)H(3))NiCl) (R = 2,6-(i)Pr(2)C(6)H(3), R' = Ph (2a) or (i)Pr (2b)), were synthesized from the reactions of bis(1,5-cyclooctadiene)nickel(0) and corresponding iminophosphinite ligands. The solid state structures of the nickel pincer complexes were determined by X-ray single crystal diffraction studies. They were successfully employed in the Kumada reaction of non-activated aryl chlorides and phenylmagnesium bromide at room temperature. (C) 2011 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.poly.2011.01.007
• 作为产物：
  描述：

  2,6-二异丙基苯胺 、 2-氯-3-羟基苯甲醛 在 甲酸 作用下， 以 乙醇 为溶剂， 反应 48.0h， 以73%的产率得到2-chloro-3-[(2,6-diisopropyl-phenylimino)methyl]phenol
  参考文献：
  名称：

  Synthesis, characterization and application of pincer-type nickel iminophosphinite complexes

  摘要：

  Two pincer-type nickel iminophosphinite complexes, [(2-(CH=NR)-6-(OPR'(2))C(6)H(3))NiCl) (R = 2,6-(i)Pr(2)C(6)H(3), R' = Ph (2a) or (i)Pr (2b)), were synthesized from the reactions of bis(1,5-cyclooctadiene)nickel(0) and corresponding iminophosphinite ligands. The solid state structures of the nickel pincer complexes were determined by X-ray single crystal diffraction studies. They were successfully employed in the Kumada reaction of non-activated aryl chlorides and phenylmagnesium bromide at room temperature. (C) 2011 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.poly.2011.01.007