2,3,8,9-tetramethyl-6H,12H-5,11-methanodibenzo<1,5>diazocine | 111437-13-9

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 二氮杂萘
• 英文名称: 2,3,8,9-tetramethyl-6H,12H-5,11-methanodibenzo<1,5>diazocine
• 英文别名: 4,5,12,13-Tetramethyl-1,9-diazatetracyclo[7.7.1.02,7.010,15]heptadeca-2(7),3,5,10(15),11,13-hexaene
• CAS: 111437-13-9
• 化学式: C₁₉H₂₂N₂
• 分子量: 278.397
• InChiKey: YGJZRQUSVCQNRV-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.6
• 重原子数：
  21
• 可旋转键数：
  0
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.37
• 拓扑面积：
  6.5
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  2,3,8,9-tetramethyl-6H,12H-5,11-methanodibenzo<1,5>diazocine 在 sodium persulfate 、 氢氟酸 、 双氧水 、 五氟化锑 作用下， 反应 0.25h， 以46%的产率得到4,5,12,13-Tetramethyl-1,9-diazatetracyclo[7.7.1.02,7.010,15]heptadeca-2(7),3,5,10(15),11,13-hexaene-6,14-diol
  参考文献：
  名称：

  使用超强酸性化学物质有效地接触Tröger的新碱

  摘要：

  在超酸性介质HF / SbF 5中，使用过硫酸钠作为氢过氧化氢H 3 O2 +前体进行了几个Tröger碱的羟基化反应。所获得的产物在芳族环的不寻常位置上以良好的产率选择性地被羟基化。

  DOI：

  10.1016/j.tetlet.2008.12.011
• 作为产物：
  描述：

  聚合甲醛 、 3,4-二甲基苯胺 在 盐酸 作用下， 以 乙醇 为溶剂， 反应 24.0h， 生成 1,2,8,9-tetramethyl-6H,12H-5,11-methanodibenzo<1,5>diazocine 、 2,3,8,9-tetramethyl-6H,12H-5,11-methanodibenzo<1,5>diazocine
  参考文献：
  名称：

  Chemistry of synthetic receptors and functional group arrays. 7. Molecular armatures. Synthesis and structure of Troeger's base analogs derived from 4-, 2,4-, 3,4-, and 2,4,5-substituted aniline derivatives

  摘要：

  DOI：

  10.1021/jo00236a020

文献信息

• Block copolymer, carbon dioxide gas separation membrane and method for manufacturing the same
  申请人：INCHEON UNIVERSITY INDUSTRY ACADEMIC COOPERATION FOUNDATION

  公开号：US10870090B2

  公开（公告）日：2020-12-22

  The present disclosure relates to a block copolymer, a carbon dioxide separation membrane using the same and a method for preparing the same. The carbon dioxide separation membrane includes a copolymer represented by the following [Chemical Formula 1], and thus has excellent thermal, chemical and mechanical stabilities and shows high selectivity and permeability to carbon dioxide.

  本公开涉及一种嵌段共聚物、使用该共聚物的二氧化碳分离膜以及制备该分离膜的方法。二氧化碳分离膜包括由下式[化学式 1]表示的共聚物，因此具有优异的热稳定性、化学稳定性和机械稳定性，并显示出对二氧化碳的高选择性和高渗透性。
• 10.1002/asia.202400513
  作者：Jaithum, Kanokwan、Tummatorn, Jumreang、Thongsornkleeb, Charnsak、Ruchirawat, Somsak

  DOI：10.1002/asia.202400513

  日期：——

  This study introduces a novel method for producing Tröger's bases by utilizing the rearrangement chemistry of benzyl azide. This method offers a convenient and adaptable pathway for synthesizing these important molecular structures with potential for further advancements. By reacting benzyl azide derivatives with TfOH under the presence of water, this process generates iminium ion, formaldehyde, and

  本研究介绍了一种利用苄基叠氮化物的重排化学来生产 Tröger 碱的新方法。该方法为合成这些重要的分子结构提供了一种方便且适应性强的途径，并具有进一步发展的潜力。通过在水存在下使苄基叠氮衍生物与 TfOH 反应，该过程原位生成亚胺离子、甲醛和苯胺中间体。值得注意的是，这种转化在酸性条件下是可逆的，允许亚胺离子再生并最终形成所需的特罗格碱产物。此外，这种方法可以降低接触过量甲醛的风险。
• Polymers, Their Method of Manufacture and Use Thereof
  申请人：McKeown Neil Bruce

  公开号：US20130172433A1

  公开（公告）日：2013-07-04

  A method for the manufacture of a polymer is provided, the method comprising: Providing a first monomer, the first monomer comprising a bicyclic diamine moiety, a first nucleophilic group provided on a carbon atom of an aromatic moiety, and a second nucleophilic group provided on a carbon atom of an aromatic moiety; Providing a bridging compound comprising at least two sites vulnerable to nucleophilic attack; and Contacting the first monomer with the bridging compound. Polymers made by said method and uses of such polymers are also disclosed.
• POLYMERS, THEIR METHOD OF MANUFACTURE AND USE THEREOF
  申请人：THE UNIVERSITY COURT OF THE UNIVERSITY OF EDINBURGH

  公开号：US20160060396A1

  公开（公告）日：2016-03-03

  A method for the manufacture of a polymer is provided, the method comprising: Providing a first monomer, the first monomer comprising a bicyclic diamine moiety, a first nucleophilic group provided on a carbon atom of an aromatic moiety, and a second nucleophilic group provided on a carbon atom of an aromatic moiety; Providing a bridging compound comprising at least two sites vulnerable to nucleophilic attack; and Contacting the first monomer with the bridging compound. Polymers made by said method and uses of such polymers are also disclosed.
• BLOCK COPOLYMER, CARBON DIOXIDE GAS SEPARATION MEMBRANE AND METHOD FOR MANUFACTURING THE SAME
  申请人：INCHEON UNIVERSITY INDUSTRY ACADEMIC COOPERATION FOUNDATION

  公开号：US20190329190A1

  公开（公告）日：2019-10-31

  The present disclosure relates to a block copolymer, a carbon dioxide separation membrane using the same and a method for preparing the same. The carbon dioxide separation membrane includes a copolymer represented by the following [Chemical Formula 1], and thus has excellent thermal, chemical and mechanical stabilities and shows high selectivity and permeability to carbon dioxide.