2-ethenyl-4,4-pentamethylene-2-oxazolin-5-one | 18500-18-0

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: 2-ethenyl-4,4-pentamethylene-2-oxazolin-5-one
• 英文别名: 2-ethenyl-4,4-pentamethylene-1,3-oxazolin-5-one；2-Ethenyl-3-oxa-1-azaspiro[4.5]dec-1-en-4-one
• CAS: 18500-18-0
• 化学式: C₁₀H₁₃NO₂
• 分子量: 179.219
• InChiKey: ONMGSQGFXZTNSI-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2
• 重原子数：
  13
• 可旋转键数：
  1
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.6
• 拓扑面积：
  38.7
• 氢给体数：
  0
• 氢受体数：
  3

文献信息

• AZETIDINIUM-CONTAINING COPOLYMERS AND USES THEREOF
  申请人：Novartis AG

  公开号：US20160326395A1

  公开（公告）日：2016-11-10

  The invention is related to azetidinium-containing copolymers and vinylic monomers and their uses in formation of non-silicone hydrogel coatings on silicone hydrogel contact lenses.

  这项发明涉及含有氮杂环丙铵的共聚物和乙烯基单体，以及它们在硅水凝胶隐形眼镜上形成非硅氧烷水凝胶涂层的用途。
• PREPOLYMERS SUITABLE FOR MAKING ULTRA-VIOLET ABSORBING CONTACT LENSES
  申请人：Domschke Angelika Maria

  公开号：US20110063567A1

  公开（公告）日：2011-03-17

  The invention provides a class of actinically-crosslinkable silicone-containing prepolymers which comprise (1) ethylenically-unsaturated groups and (2) UV-absorbing polymeric units, latent UV-absorbing polymeric units, and/or dual photo-functional polymeric units. The prepolymer of the invention can be used to prepare silicone hydrogel contact lenses capable of absorbing UV/visible radiation. The present invention is also related to silicone hydrogel contact lenses made from a prepolymer of the invention and methods for making the contact lenses in a cost-effective way and with high consistency and high fidelity to the original lens design.

  本发明提供一类光致交联硅含量预聚物，其包括（1）乙烯基-不饱和基团和（2）紫外线吸收聚合物单元、潜在紫外线吸收聚合物单元和/或双重光功能聚合物单元。本发明的预聚物可用于制备能够吸收紫外线/可见光辐射的硅水凝胶隐形眼镜。本发明还涉及使用本发明预聚物制造硅水凝胶隐形眼镜的方法，以成本效益高、一致性高和对原始镜片设计的高度忠实。
• Method of hydrophilizing or hydrophobizing polymers
  申请人：MINNESOTA MINING AND MANUFACTURING COMPANY

  公开号：EP0105666A1

  公开（公告）日：1984-04-18

  A method of modifying the overall hydrophilic or hydrophobic nature of a high molecular weight free radical addition interpolymer, which is an aziactone-functional interpolymer, with a hydrophilic or hydrophobic nucleophilic compound is disclosed. Only the surface of the interpolymer can be hydrophilized or hydrophobized, as when the interpolymer is a coating, or the modification can take place throughout the entire bulk of the interpolymer.

  本发明公开了一种用亲水或疏水的亲核化合物改性高分子量自由基加成互聚物（叠氮酮官能团互聚物）的整体亲水性或疏水性的方法。可以只对互聚物的表面进行亲水或疏水处理（如互聚物是涂层时），也可以对互聚物的整个主体进行改性。
• Azlactone-containing pressure-sensitive adhesives
  申请人：MINNESOTA MINING AND MANUFACTURING COMPANY

  公开号：EP0128731A1

  公开（公告）日：1984-12-19

  Pressure-sensitive adhesives are prepared by the simultaneous polymerization of minor amounts of at least one alkenyl azlactone monomer and at least one arylic-functional carboxylic acid monomer, or precursors thereof, with a major amount of at least one acrylic monomer. The pressure-sensitive adhesives, after application to a substrate, will significantly increase in adhesion to the resultant bonded substrate after they are in the bonded configuration.

  压敏型粘合剂的制备方法是将少量的至少一种烯基氮内酯单体和至少一种丙烯酸官能团羧酸单体或其前体与大量的至少一种丙烯酸单体同时聚合。压敏粘合剂涂抹到基材上后，在粘合状态下，与粘合基材的粘合力会明显增强。
• Azlactone graft copolymers
  申请人：MINNESOTA MINING AND MANUFACTURING COMPANY

  公开号：EP0392783A2

  公开（公告）日：1990-10-17

  Graft copolymers and processes for the preparation thereof are provided. The copolymers comprise a base polymer having grafted thereto a monomeric 2-alkenyl azlactone. The surface properties of the graft copolymers can be modified by binding thereto nucleophilic reagents comprising further functional groups with desired properties. Further, the amount of azlactone available at the surface of a graft copolymer for binding to such nucleophilic reagents can be controlled by selecting a surface against which the graft copolymer is formed. The graft copolymers exhibit desirable thermoplastic, melt flow, and adhesion properties and are particularly useful for immobilizing proteins. Methods of immunoassay based on the immobilization of proteins are also disclosed. Another utility of the graft copolymers involves the compatibilizing of immiscible polymer blends.

  提供了接枝共聚物及其制备工艺。这种共聚物包括一种接枝了 2-烯基氮内酯单体的基础聚合物。接枝共聚物的表面性质可通过与亲核试剂结合而改变，亲核试剂包括具有所需性质的其他官能团。此外，接枝共聚物表面可用于与此类亲核试剂结合的氮内酯量可通过选择形成接枝共聚物的表面来控制。接枝共聚物具有理想的热塑性、熔融流动性和粘附性，特别适用于固定蛋白质。此外，还公开了基于固定蛋白质的免疫测定方法。接枝共聚物的另一个用途是使不相溶的聚合物混合物相容。