2-allyl-1,3-dioxo-indan-2-carboxylic acid ethyl ester | 859769-37-2

• 分子结构分类: 有机化合物 - 苯类化合物 - 茚满类
• 英文名称: 2-allyl-1,3-dioxo-indan-2-carboxylic acid ethyl ester
• 英文别名: 2-Allyl-1,3-dioxo-indan-2-carbonsaeure-aethylester；1.3-Dioxo-2-allyl-hydrinden-carbonsaeure-(2)-aethylester；2-Allyl-indandion-(1.3)-carbonsaeure-(2)-aethylester；Ethyl 2-allyl-1,3-dioxo-2,3-di-hydro-1h-indene-2-carboxylate；ethyl 1,3-dioxo-2-prop-2-enylindene-2-carboxylate
• CAS: 859769-37-2
• 化学式: C₁₅H₁₄O₄
• 分子量: 258.274
• InChiKey: IFYNXDNKJAFUHA-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.8
• 重原子数：
  19
• 可旋转键数：
  5
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.27
• 拓扑面积：
  60.4
• 氢给体数：
  0
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  2-allyl-1,3-dioxo-indan-2-carboxylic acid ethyl ester 在 氯仿 、 溴 作用下， 生成 5-bromomethyl-4,5-dihydro-spiro[furan-3,2'-indan]-2,1',3'-trione
  参考文献：
  名称：

  Radulescu, Bulletin de la Societe Chimique de France, 1925, vol. <4> 37, p. 917

  摘要：

  DOI：
• 作为产物：
  描述：

  丙烯酰碘 、 alkaline earth salt of/the/ methylsulfuric acid 在 乙醇 作用下， 生成 2-allyl-1,3-dioxo-indan-2-carboxylic acid ethyl ester
  参考文献：
  名称：

  Radulescu, Bulletin de la Societe Chimique de France, 1925, vol. <4> 37, p. 917

  摘要：

  DOI：

文献信息

• Unusual early bile excretion from the liver in patients with fulminant hepatic failure as detected by Tc-99m-PMT hepatobiliary scintigraphy; Comparison with Tc-99m-GSA scintigraphy
  作者：Shin Matsuoka、Katsuhiro Uchiyama、Yoshio Kuniyasu、Yasuo Niio、Shin Hasebe、Hideki Shima、Sonomi Oishi、Youko Nojiri、Hitoshi Ogata

  DOI：10.1007/bf03012133

  日期：2001.2

  In two females (58 and 14 years old) with fulminant hepatic failure, Tc-99m-PMT hepatobiliary scintigraphy was used to evaluate intrahepatic bile stagnation, and Tc-99m-GSA scintigraphy to evaluate hepatic functional reserve. In both patients, Tc-99m-PMT hepatobiliary scintigraphy showed unusual early bile excretion into the extrahepatic bile duct and small intestine within the first 30 min of imaging. These findings contradicted typical findings of intrahepatic bile stagnation of fulminant hepatic failure. The receptor index and blood clearance index determined from dynamic acquisition data on Tc-99m-GSA scintigraphy suggested a markedly decreased hepatic functional reserve. These findings were compatible with fulminant hepatic failure. A discrepancy was observed between the findings of hepatobiliary scintigraphy and those of Tc-99m-GSA scintigraphy. The pathological state of early bile excretion from the liver into the bile duct should be considered in fulminant hepatic failure.
• Radulescu; Moga, 1939, vol. <2> 1, p. 18,21
  作者：Radulescu、Moga

  DOI：——

  日期：——