N-benzyl-3-dichloromethyl-5-methylhexanamide | 1144854-27-2

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: N-benzyl-3-dichloromethyl-5-methylhexanamide
• 英文别名: N-benzyl-3-(dichloromethyl)-5-methylhexanamide
• CAS: 1144854-27-2
• 化学式: C₁₅H₂₁Cl₂NO
• 分子量: 302.244
• InChiKey: LIWNRHZEXBLTPO-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.3
• 重原子数：
  19
• 可旋转键数：
  7
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.53
• 拓扑面积：
  29.1
• 氢给体数：
  1
• 氢受体数：
  1

文献信息

• Pregabalin intermediates and process for preparing them and Pregabalin
  申请人：Chemo Ibérica, S.A.

  公开号：EP2053040A1

  公开（公告）日：2009-04-29

  The present invention provides novel compounds, which are especially useful as intermediates for the preparation of Pregabalin. The invention also relates to process for preparing these intermediates and Pregabalin.

  本发明提供了新型化合物，它们尤其可用作制备普瑞巴林的中间体。本发明还涉及制备这些中间体和普瑞巴林的工艺。
• [EN] NOVEL PREGABALIN INTERMEDIATES AND PROCESS FOR PREPARING THEM AND PREGABALIN<br/>[FR] NOUVEAUX INTERMÉDIAIRES DE PRÉGABALINE ET PROCÉDÉ DE PRÉPARATION DESDITS INTERMÉDIAIRES ET DE PRÉGABALINE
  申请人：CHEMO IBERICA SA

  公开号：WO2009053446A2

  公开（公告）日：2009-04-30

  The present invention provides novel compounds, which are especially useful as intermediates for the preparation of Pregabalin. The invention also relates to process for preparing these intermediates and Pregabalin.