4-羟基-5-甲氧基邻苯二甲酸 | 63035-28-9

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 中文名称: 4-羟基-5-甲氧基邻苯二甲酸
• 英文名称: 4-hydroxy-5-methoxy-phthalic acid
• 英文别名: 4-Hydroxy-5-methoxy-phthalsaeure；Normetahemipinsaeure-monomethylaether；4-Oxy-5-methoxy-phthalsaeure；6-Carboxyvanillic acid；4-hydroxy-5-methoxyphthalic acid
• CAS: 63035-28-9
• 化学式: C₉H₈O₆
• 分子量: 212.159
• InChiKey: OFECJXVRRIHUSC-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.6
• 重原子数：
  15
• 可旋转键数：
  3
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.11
• 拓扑面积：
  104
• 氢给体数：
  3
• 氢受体数：
  6

反应信息

• 作为反应物：
  描述：

  4-羟基-5-甲氧基邻苯二甲酸 在 溴 、 溶剂黄146 作用下， 生成 3-bromo-4-hydroxy-5-methoxy-phthalic acid
  参考文献：
  名称：

  Faltis; Frauendorfer, Chemische Berichte, 1930, vol. 63, p. 815

  摘要：

  DOI：
• 作为产物：
  描述：

  4,5-二甲氧基邻苯二甲酸 在 盐酸 作用下， 生成 4-羟基-5-甲氧基邻苯二甲酸
  参考文献：
  名称：

  Spaeth; Duschinsky, Chemische Berichte, 1925, vol. 58, p. 1946

  摘要：

  DOI：

文献信息

• King, Journal of the Chemical Society, 1939, p. 1159
  作者：King

  DOI：——

  日期：——
• Spaeth; Duschinsky, Chemische Berichte, 1925, vol. 58, p. 1946
  作者：Spaeth、Duschinsky

  DOI：——

  日期：——
• Aiding chronic written language expression difficulties: A case study
  作者：Linda Armstrong、Alison Macdonald

  DOI：10.1080/026870300401612

  日期：2000.1

  This paper describes some progress made in helping a young aphasic man (MD) to overcome what had appeared to be intractable written language expression difficulties, which continued to be significant for him. Traditional therapy methods based on cognitive neuropsychological assessment had failed to help MD to generalize improvement in his spelling particularly, but not exclusively, of longer and irregular words. Both a splint which allowed him to use his dominant hand for writing directly onto a computer screen and a simple word-processing programme with synthesized auditory feedback and lexical and grammatical prediction (Write:OutLoud(R) and Co:Writer(R)) enabled him to produce more normal written output (increased quantity and more normal quality). The discussion also focuses on how effectiveness of language therapy can be measured in this man with chronic aphasia.
• Faltis; Frauendorfer, Chemische Berichte, 1930, vol. 63, p. 815
  作者：Faltis、Frauendorfer

  DOI：——

  日期：——