1-tert-butyl-3,4-diisopropyl-pyrrole | 54697-80-2

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡咯
• 英文名称: 1-tert-butyl-3,4-diisopropyl-pyrrole
• 英文别名: 1-Tert-butyl-3,4-di(propan-2-yl)pyrrole
• CAS: 54697-80-2
• 化学式: C₁₄H₂₅N
• 分子量: 207.359
• InChiKey: BCUXNTUNIWQMGQ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.8
• 重原子数：
  15
• 可旋转键数：
  3
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.71
• 拓扑面积：
  4.9
• 氢给体数：
  0
• 氢受体数：
  0

文献信息

• Opiate analogs selective for the delta-opioid receptor
  申请人：Welsh J. William

  公开号：US20070105884A1

  公开（公告）日：2007-05-10

  Novel compounds which selectively bind to the δ-opioid receptor have been designed. These compounds have greater selectivity, improved water (blood) solubility, and enhanced therapeutic value as analgesics. Because agonists with selectivity for the δ-opioid receptor have shown promise in providing enhanced analgesis without the addictive properties, the compounds of the present invention are better than morphine, naltrindole (NTI), spiroindanyloxymorphone (SIOM), and other known μ-opioid receptor selectors as analgesics.