2,5-dioxopyrrolidin-1-yl 3,5-bis(3-{3,5-bis[3-(tert-butyloxycarbonylamino)propyloxy]benzoylamino}propyloxy)benzoate | 1294446-67-5

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 2,5-dioxopyrrolidin-1-yl 3,5-bis(3-{3,5-bis[3-(tert-butyloxycarbonylamino)propyloxy]benzoylamino}propyloxy)benzoate
• 英文别名: (2,5-Dioxopyrrolidin-1-yl) 3,5-bis[3-[[3,5-bis[3-[(2-methylpropan-2-yl)oxycarbonylamino]propoxy]benzoyl]amino]propoxy]benzoate
• CAS: 1294446-67-5
• 化学式: C₆₃H₉₁N₇O₂₀
• 分子量: 1266.45
• InChiKey: PFHPBZYYSFHLSK-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  7.6
• 重原子数：
  90
• 可旋转键数：
  43
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.57
• 拓扑面积：
  331
• 氢给体数：
  6
• 氢受体数：
  20

反应信息

• 作为产物：
  描述：

  N-羟基丁二酰亚胺 、 3,5-Bis[3-[[3,5-bis[3-[(2-methylpropan-2-yl)oxycarbonylamino]propoxy]benzoyl]amino]propoxy]benzoic acid 在 盐酸-N-乙基-Nˊ-(3-二甲氨基丙基)碳二亚胺 作用下， 以 二氯甲烷 、 N,N-二甲基甲酰胺 为溶剂， 反应 24.0h， 以80%的产率得到2,5-dioxopyrrolidin-1-yl 3,5-bis(3-{3,5-bis[3-(tert-butyloxycarbonylamino)propyloxy]benzoylamino}propyloxy)benzoate
  参考文献：
  名称：

  Kinetics of Free Radical Polymerization of Spacerless Dendronized Macromonomers in Supercritical Carbon Dioxide

  摘要：

  The kinetics of the free radical polymerization in supercritical carbon dioxide of third (G3) and fourth (G4) generation spacerless dendronized macromonomers, bearing a methacrylate group at the focal point, is experimentally investigated. Conversions up to 90% could be achieved in few hours for both monomers, with degrees of polymerization on the order of thousands of monomer units for G3 and 100-200 for G4. Experimental data are interpreted using a conventional free radical kinetic scheme. Within this frame, chain termination is dominated by chain transfer to monomer and the extremely high reactivity of the macromonomers when polymerized in supercritical carbon dioxide is reflecting reduced termination rate at increasing dendron generation.

  DOI：

  10.1021/ma2002189