Z-D-Ala-D-Ala-OB | 94943-34-7

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: Z-D-Ala-D-Ala-OB
• 英文别名: benzyl (2R)-2-[[(2R)-2-(phenylmethoxycarbonylamino)propanoyl]amino]propanoate
• CAS: 94943-34-7
• 化学式: C₂₁H₂₄N₂O₅
• 分子量: 384.432
• InChiKey: UVFGJKZMNXFIME-HZPDHXFCSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3
• 重原子数：
  28
• 可旋转键数：
  10
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.29
• 拓扑面积：
  93.7
• 氢给体数：
  2
• 氢受体数：
  5

文献信息

• [EN] A NEW THERMOSTABLE D-STEREOSPECIFIC DIPEPTIDASE FROM BREVIBACILLUS BOSTELENSIS BCS-1 AND ITS USE AS A BIOCATALYST FOR THE SYNTHESIS OF PEPTIDES CONTAINING D-AMINO ACIDS<br/>[FR] NOUVELLE DIPEPTIDASE D-STEREOSPECIFIQUE THERMOSTABLE ISSUE DE BREVIBACILLUS BORSTELENSIS BCS-1 ET SON UTILISATION COMME BIOCATALYSEUR POUR LA SYNTHESE DE PEPTIDES CONTENANT DES ACIDES AMINES D
  申请人：KOREA RES INST OF BIOSCIENCE

  公开号：WO2001070937A1

  公开（公告）日：2001-09-27

  The present invention relates to a new D-stereospecific dipeptidase derived from Brevibacillus borstelensis BCS-1 (Accession NO: KCTC 0673BP) and use of the new dipeptidase as a biocatalyst for the synthesis of peptides containing D-amino acid. Particularly, the present invention relates to a new D-stereospecific dipeptidase from Brevibacillus borstelensis BCS-1 selected by screening diverse enzymes hydrolyzing D-peptide derivatives, a gene encoding the dipeptidase, a recombinant vector containing the gene, a microorganism transformed by the vector, the enzyme characteristics (thermostability, pH stability and substrate stability), and a method for synthesis of D-amino acid-containing peptide economically and without environmental pollution.