4-芘-1-基丁酸钠 | 63442-80-8

• 分子结构分类: 有机化合物 - 苯类化合物 - 芘
• 中文名称: 4-芘-1-基丁酸钠
• 英文名称: sodium 1-pyrenebutyrate
• 英文别名: Sodium 4-pyrenylbutanoate；sodium;4-pyren-1-ylbutanoate
• CAS: 63442-80-8
• 化学式: C₂₀H₁₅O₂*Na
• 分子量: 310.328
• InChiKey: FUKSLCXVXNNQLX-UHFFFAOYSA-M

计算性质

• 辛醇/水分配系数(LogP)：
  0.66
• 重原子数：
  23
• 可旋转键数：
  4
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.15
• 拓扑面积：
  40.1
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  N-[13-[[hydroxy-[3,4,5-tris[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]phenyl]methylidene]amino]-5,7,12,14-tetraoxo-6,13-diazatetracyclo[6.6.2.04,16.011,15]hexadeca-1(15),2,4(16),8,10-pentaen-6-yl]-3,4,5-tris[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]benzenecarboximidic acid 、 4-芘-1-基丁酸钠 以 水 为溶剂， 生成
  参考文献：
  名称：

  氢键介导的功能化萘二酰亚胺基双亲苯的水泡组装及客体诱导的凝胶化

  摘要：

  本文利用π堆积和氢键的协同效应描述了基于萘二酰亚胺（NDI）的非离子型双亲两性水相在水介质中的自发囊泡组装。在系统中执行了氢键官能团（酰肼）的位点隔离，这种策略本质上已被巧妙地采用，可以保护这些部分不受大量水的影响，从而使氢键在自组装过程中发挥独特作用即使在水溶液中，也可以实现酰肼官能化的NDI构建基块。此外，缺电子的基于NDI的两亲分子可通过在两个NDI之间插入后一种生色团而与不溶于水的富电子pyr供体进行供体-受体（DA）电荷转移（CT）相互作用。建筑模块。值得注意的是 即使pyr位于两个NDI嵌段之间，也可以保留NDI连接的酰肼基团之间的分子间氢键网络。然而，随时间变化的原子力显微镜研究表明，交替堆叠的D–A组件的曲率半径显着增加，从而导致囊泡间融合，最终导致膜破裂而形成一维纤维。这种从2D到1D的形态学转变产生了相对较高浓度的CT介导的水凝胶。ζ电位测量证明，当使用水溶性羧酸盐官能

  DOI：

  10.1002/chem.201201299
• 作为产物：
  描述：

  1-芘丁酸 在 sodium hydroxide 作用下， 以 水 为溶剂， 生成 4-芘-1-基丁酸钠
  参考文献：
  名称：

  Simultaneous Noncovalent Modification and Exfoliation of 2D Carbon Nitride for Enhanced Electrochemiluminescent Biosensing

  摘要：

  As an emerging nitrogen-rich 2D carbon material, graphitic carbon nitride (CN) has drawn much attention for applications ranging from photo-/electrocatalysts to biosensors. Interfacial modification of CN is fundamentally vital but is still in, its infancy and remains challenging due to the low reactivity of CN. Here we report that, in conjunction with a pi-pi stacking interaction, bulk CN could be simultaneously exfoliated via facile mechanical grinding. The obtained CN nanosheets (m-CNNS) not only retained the pristine optoelectronic properties of bulk CN but also enriched a friendly interface for further coupling biomolecules with advanced properties, overcoming the deficiencies of CN in surface science. The m-CNNS were further covalently linked to a DNA probe, and the resultant electrochemiluminescent biosensor for the target DNA exhibited much enhanced sensitivity with respect to that obtained by direct physical absorption of the DNA probe on unmodified CNNS. This noncovalent exfoliation and interfacial modification should greatly expand the scope of potential applications of CN in areas such as biosensing and should also be applicable to other 2D materials in interface modulation.

  DOI：

  10.1021/jacs.7b06708

文献信息

• Design and synthesis of dual probes for detection of metal ions by LALDI MS and fluorescence: application in Zn(<scp>ii</scp>) imaging in cells
  作者：Arundhoti Mandal Arundhoti Mandal、Asim Maity、Swarnendu Bag、Prabuddha Bhattacharya、Amit K. Das、Amit Basak

  DOI：10.1039/c6ra27302e

  日期：——

  metal ions through a time of flight (TOF) mass spectrometric measurement. In this paper, we report the synthesis of two terpyridine based ligands L1 and L2 containing a pyrene moiety. The presence of the latter helped the ligand metal complex to desorb from the surface and ionize upon laser irradiation and finally show up in the TOF MS. Both ligands were able to detect Zn2+, Ni2+ and Co2+ ions while

  最近，一种标签辅助激光解吸/电离（LALDI）技术已通过飞行时间（TOF）质谱测量技术应用于金属离子的检测。在本文中，我们报告了两个基于a的含a部分的配体L1和L2的合成。后者的存在帮助配体金属络合物从表面解吸并在激光照射下电离，最后出现在TOF MS中。两种配体都能够检测到Zn 2 +，Ni 2+和Co 2+离子，而Cu 2 +，Fe 2+和Mg 2+仍然保持LDI沉默。与配体的络合也仅与Zn一起引起红色荧光2+离子可在细胞中进行Zn 2+成像。因此，L部分利用LALDI MS和荧光技术充当了金属离子检测的双重探针。
• Inclusion complexes of pyrenylbutyrate with γ-cyclodextrin
  作者：William G. Herkstroeter、Peter A. Martic、Samir Farid

  DOI：10.1039/p29840001453

  日期：——

  4-pyren-1-ylbutyrate ion with γ-cyclodextrin in aqueous solution leads to inclusion complexes that become evident from changed absorption spectra as well as protection of the included pyrene moieties from fluorescence quenchers. The inclusion proceeds in stages, yielding first a 1:1 complex, which then dimerizes to form a 2:2 complex. At 25 °C the respective equilibrium constants of complex formation are 1.3 ×

  在水溶液中将4-pyren-1-ylbutyrate离子与γ-环糊精混合会导致包合物形成，这从吸收光谱的变化以及对包含的pyr部分的荧光猝灭剂的保护中可以明显看出。包涵体分阶段进行，首先产生1：1的络合物，然后二聚化形成2：2的络合物。在25°C时，复合物形成的各个平衡常数分别为1.3×10 3和5.2×10 4 l mol –1。二聚平衡具有不寻常的温度依赖性，ΔH ≠ –16.7 kcal mol –1，ΔS ≠ –35 cal K –1 mol –1。
• Cyclodextrin inclusion complexes of 1-pyrenebutyrate. The role of coinclusion of amphiphiles
  作者：William G. Herkstroeter、Peter A. Martic、Ted R. Evans、Samir. Farid

  DOI：10.1021/ja00272a022

  日期：1986.6
• EP0543896A4
  申请人：——

  公开号：EP0543896A4

  公开（公告）日：1994-10-19
• IN VIVO MEASUREMENT OF OXYGEN CONCENTRATION LEVELS
  申请人：DREXEL UNIVERSITY

  公开号：EP0543896A1

  公开（公告）日：1993-06-02