silver adipate | 73603-96-0

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: silver adipate
• 英文别名: siver adipate；Ag2(adipate)；adipic acid ; silver adipate；Adipinsaeure; Silberadipat；Adipinsaeure; Disilber(I)-Verbindung；silver;hexanedioate
• CAS: 73603-96-0
• 化学式: 2Ag*C₆H₈O₄
• 分子量: 359.864
• InChiKey: IKKSKJIOBLPPKK-UHFFFAOYSA-L

计算性质

• 辛醇/水分配系数(LogP)：
  -1.96
• 重原子数：
  11.0
• 可旋转键数：
  5.0
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.67
• 拓扑面积：
  80.26
• 氢给体数：
  0.0
• 氢受体数：
  4.0

反应信息

• 作为反应物：
  描述：

  silver adipate 在 三苯基膦 作用下， 以 乙醇 为溶剂， 生成
  参考文献：
  名称：

  第1B组的金属络合物。第1部分。三苯基膦银（I）羧酸盐

  摘要：

  已经研究了羧酸与Ag I的配位方式。通过对1 H nmr和ir光谱以及溶液分子量的研究，络合物中的银原子都是四坐标的，但化学计量学取决于酸的p K a。所有被研究的stoicheiometry形成复合物将[Ag（O酸2 CR）（PPH 3）2 ]（R = Me中，CH 2氯，三氯甲烷2中，Ph，C 6 H ^ 4 ME- ø，C 6 H ^ 4 ME-米或C 6 H 4 OH-o）。此外，对于具有p酸ķ一个> 3.9（即R =我中，Ph，C 6 H ^ 4 ME- Ò，或C 6 H ^ 4 ME-米）的酸到银结果在复杂storcheiometry的螯合[ Ag（O 2 CR）（PPh 3）2 ]。所研究的两种二元酸，己二酸和丙二酸，显示出相似的p K a依赖性。

  DOI：

  10.1039/dt9770002068
• 作为产物：
  描述：

  Adipic acid dipotassium salt 、 silver nitrate 生成 silver adipate
  参考文献：
  名称：

  Dash, Upendra Nath; Nayak, Uttam Kumar, Canadian Journal of Chemistry, 1980, vol. 58, # 4, p. 323 - 327

  摘要：

  DOI：

文献信息

• Water-soluble and photo-stable silver(I) dicarboxylate complexes containing 1,10-phenanthroline ligands: Antimicrobial and anticancer chemotherapeutic potential, DNA interactions and antioxidant activity
  作者：Laura Thornton、Vidya Dixit、Letícia O.N. Assad、Thales P. Ribeiro、Daniela D. Queiroz、Andrew Kellett、Alan Casey、John Colleran、Marcos D. Pereira、Garret Rochford、Malachy McCann、Denis O'Shea、Rita Dempsey、Siobhán McClean、Agnieszka Foltyn-Arfa Kia、Maureen Walsh、Bernadette Creaven、Orla Howe、Michael Devereux

  DOI：10.1016/j.jinorgbio.2016.02.024

  日期：2016.6

  studies indicate that the mechanism of action of 11-20 is significantly different to that of their silver(I) dicarboxylate precursors and they do not induce DNA damage or ROS generation in mammalian cells. The representative complexes 9 and 19 (containing the undecanedioate ligand) were both found to significantly reduce superoxide and hydrogen peroxide induced oxidative stress in the yeast S. cerevisiae

  合成配合物[Ag2（OOC-（CH2）n-COO）]（n = 1-10）（1-10）并与1,10-菲咯啉（phen）反应生成衍生物，公式为[Ag2（phen） x（OOC-（ ）y-COO）]。zH2O（x = 2或3; y = 1-10; z = 1-4）（11-20），在水中高度水溶性且光稳定解决方案。phen衍生物11-20对白色念珠菌，大肠杆菌，金黄色葡萄球菌和铜绿假单胞菌以及对顺铂敏感的乳腺癌（MCF-7）和耐药的卵巢癌（SKOV-3）癌细胞系均具有化学治疗潜力。循环伏安分析以及DNA结合和嵌入研究表明11-20的作用机理与它们的二羧酸银（I）前体的作用机理显着不同，并且它们不会在哺乳动物细胞中诱导DNA损伤或ROS生成。
• Toward Designed Assembly of Microporous Coordination Networks Constructed from Silver(I)−Hexamethylenetetramine Layers
  作者：Shao-Liang Zheng、Ming-Liang Tong、Ruo-Wen Fu、Xiao-Ming Chen、Seik-Weng Ng

  DOI：10.1021/ic001237z

  日期：2001.7.1

  Eight interesting microporous networks based on 2-D [Ag(mu -hmt)] (hmt = hexamethyleneretramine) layers were obtained via rational synthetic strategies. Out of these products isolated and structurally characterized, six present a metal-to-hmt molar ratio of 1:1 and contain 2-D coordination layers assembled by 2-D Ag(I)-hmt networks with aromatic monocarboxylates, which are [Ag(mu (3)-hmt)(p-nba)].2.5H(2)O (1), [Ag(mu (3)-hmt)(m-nba)].2.5H(2)O (2), [Ag(mu -hmt)(dnba)] (3), [Ag(mu (3)-hmt)(alpha -hna)](EtOH) (4), [Ag(mu (3)-hmt)(beta -hna)](EtOH) (5), and [Ag(mu (3)-hmt)(noa)]-(H2O)(EtOH) (6) (p-nba = 4-nitrobenzoate, m-nba = 3-nitrobenzoate, dnba = 3,5-dinitrubenzoate, alpha -hna = 1-hydroxy-2-naphthate, beta -hna = 3-hydroxy-2-naphthate, and noa = 2-naphthoxyacetate), and two present a metal-to-hmt molar ratio of 2:1 and contain 3-D microporous networks constructed from thr 2-D Ag-hmt layers and linear dicarboxylates as molecular pillars, which are [Ag-2(mu (3)-hmt)(2)(fa)]. 4H(2)O (7) and [Ag-2(mu (3)-hmt)(2)(adp)]. 8H(2)O (8) (fa = fumarate and adp = adipate). The result shows that the pore sizes may be tuned with different carboxylates. Gas adsorption measurements were performed to confirm the microporosity of these coordination open frameworks.