tris[3-(4-aminobenzyloxy)propyl]phosphine oxide | 476213-98-6

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: tris[3-(4-aminobenzyloxy)propyl]phosphine oxide
• 英文别名: 4-[3-[Bis[3-[(4-aminophenyl)methoxy]propyl]phosphoryl]propoxymethyl]aniline；4-[3-[bis[3-[(4-aminophenyl)methoxy]propyl]phosphoryl]propoxymethyl]aniline
• CAS: 476213-98-6
• 化学式: C₃₀H₄₂N₃O₄P
• 分子量: 539.655
• InChiKey: TWSDCTVHGLVFHX-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.4
• 重原子数：
  38
• 可旋转键数：
  18
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.4
• 拓扑面积：
  123
• 氢给体数：
  3
• 氢受体数：
  7

反应信息

• 作为反应物：
  描述：

  2-(((2S,3S,4S,5R,6R)-3,4,5-triacetoxy-6-(acetoxymethyl)tetrahydro-2H-pyran-2-yl)oxy)acetic acid 、 tris[3-(4-aminobenzyloxy)propyl]phosphine oxide 在 1-羟基苯并三唑 、 O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate 、 N,N-二异丙基乙胺 作用下， 以 N,N-二甲基甲酰胺 为溶剂， 以80%的产率得到
  参考文献：
  名称：

  SYNTHESIS OF HYDROPHILIC ULTRAFINE NANOPARTICLES COORDINATED WITH CARBOHYDRATE CLUSTER

  摘要：

  A hydrophilic phosphine oxide (1) as a suitable ligand for semiconductor nanoparticles was synthesized. The hydrophilicity of the phosphine oxide was enhanced by introduction of three mannose moieties to the end of the molecule via amide linkages. The ligand 1 was able to coordinate to the CdSe/ZnS nanoparticle making the newly formed hydrophilic complex.

  DOI：

  10.1081/car-120014905
• 作为产物：
  描述：

  三(3-羟基丙基)氧化膦 在 silver(l) oxide 、 锌 作用下， 以 二氯甲烷 、 水 、 溶剂黄146 为溶剂， 反应 72.0h， 生成 tris[3-(4-aminobenzyloxy)propyl]phosphine oxide
  参考文献：
  名称：

  SYNTHESIS OF HYDROPHILIC ULTRAFINE NANOPARTICLES COORDINATED WITH CARBOHYDRATE CLUSTER

  摘要：

  A hydrophilic phosphine oxide (1) as a suitable ligand for semiconductor nanoparticles was synthesized. The hydrophilicity of the phosphine oxide was enhanced by introduction of three mannose moieties to the end of the molecule via amide linkages. The ligand 1 was able to coordinate to the CdSe/ZnS nanoparticle making the newly formed hydrophilic complex.

  DOI：

  10.1081/car-120014905

文献信息

• SYNTHESIS OF HYDROPHILIC ULTRAFINE NANOPARTICLES COORDINATED WITH CARBOHYDRATE CLUSTER
  作者：Jun-ichi Tamura、Masumi Fukuda、Junko Tanaka、Manabu Kawa

  DOI：10.1081/car-120014905

  日期：2002.1.10

  A hydrophilic phosphine oxide (1) as a suitable ligand for semiconductor nanoparticles was synthesized. The hydrophilicity of the phosphine oxide was enhanced by introduction of three mannose moieties to the end of the molecule via amide linkages. The ligand 1 was able to coordinate to the CdSe/ZnS nanoparticle making the newly formed hydrophilic complex.