1-hexyl-2-(4-hydroxy-3-methoxyphenyl)-6-[(E)-2-(4-hydroxy-3-methoxyphenyl)ethenyl]-2,3-dihydropyridin-4-one | 1030900-39-0

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 二芳基庚烷
• 英文名称: 1-hexyl-2-(4-hydroxy-3-methoxyphenyl)-6-[(E)-2-(4-hydroxy-3-methoxyphenyl)ethenyl]-2,3-dihydropyridin-4-one
• CAS: 1030900-39-0
• 化学式: C₂₇H₃₃NO₅
• 分子量: 451.563
• InChiKey: WQGOUCPQFCIKTC-DHZHZOJOSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.5
• 重原子数：
  33
• 可旋转键数：
  10
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.37
• 拓扑面积：
  79.2
• 氢给体数：
  2
• 氢受体数：
  6

反应信息

• 作为产物：
  描述：

  正己胺 、 姜黄素 在 montmorillonite K-10 作用下， 以7%的产率得到1-hexyl-2-(4-hydroxy-3-methoxyphenyl)-6-[(E)-2-(4-hydroxy-3-methoxyphenyl)ethenyl]-2,3-dihydropyridin-4-one
  参考文献：
  名称：

  Microwave-assisted synthesis of dihydropyridones from curcumin

  摘要：

  Dihydropyridones were prepared by microwave-assisted reaction between curcurnin and primary amines or their acetates in the presence of Montmorillonite (K-10) as a catalyst. The reaction was complete within a few minutes and the yield depends on the amine used. (C) 2008 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2008.03.064

文献信息

• Microwave-assisted synthesis of dihydropyridones from curcumin
  作者：Rita S. Elias、Bahjat A. Saeed、Kawkab Y. Saour、Najim A. Al-Masoudi

  DOI：10.1016/j.tetlet.2008.03.064

  日期：2008.5

  Dihydropyridones were prepared by microwave-assisted reaction between curcurnin and primary amines or their acetates in the presence of Montmorillonite (K-10) as a catalyst. The reaction was complete within a few minutes and the yield depends on the amine used. (C) 2008 Elsevier Ltd. All rights reserved.