1,2,4,5-tetrakis(1-ethylpropyl)benzene | 265132-58-9

• 分子结构分类: 有机化合物
• 英文名称: 1,2,4,5-tetrakis(1-ethylpropyl)benzene
• 英文别名: 1,2,4,5-tetrakis(3-pentyl)benzene；1,2,4,5-Tetra(pentan-3-yl)benzene
• CAS: 265132-58-9
• 化学式: C₂₆H₄₆
• 分子量: 358.651
• InChiKey: ORYCYVVWLSQTNZ-UHFFFAOYSA-N

物化性质

• 沸点：
  413.4±40.0 °C(Predicted)
• 密度：
  0.850±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  10.8
• 重原子数：
  26
• 可旋转键数：
  12
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.77
• 拓扑面积：
  0
• 氢给体数：
  0
• 氢受体数：
  0

反应信息

• 作为反应物：
  描述：

  1,2,4,5-tetrakis(1-ethylpropyl)benzene 在 正丁基锂 作用下， 以 四氢呋喃 为溶剂， 反应 1.5h， 生成 1,2,4,5-Tetrakis-(1-ethyl-propyl)-3-methylsulfanyl-benzene
  参考文献：
  名称：

  Synthesis and properties of 1-bromo-2,3,5,6-tetrakis(3-pentyl)benzene: a highly sterically hindered aryl bromide

  摘要：

  The preparation of 1-bromo-2,3,5,6-tetrakis(3-pentyl)benzene is reported. The H-1 and C-13 NMR spectra indicate the presence of rotational isomers at room temperature which interconvert on heating. Coalescence of the NMR peaks for the methine and methylene aliphatic protons is observed at 100-120degreesC. The conversion of this aryl bromide to the corresponding aryllithium is reported. Similar but less bulky aryl bromides have also been synthesised. (C) 2004 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2004.10.144
• 作为产物：
  描述：

  乙烯 、 1,2,4,5-四甲苯 在 正丁基锂 、 LiK(OCH₂CH₂NMe₂)2 、 magnesium(2-ethoxyethylate)2 作用下， 以 various solvent(s) 为溶剂， 20.0~80.0 ℃ 、2.03 MPa 条件下， 反应 24.5h， 以60%的产率得到1,2,4,5-tetrakis(1-ethylpropyl)benzene
  参考文献：
  名称：

  乙烯对芳烃的化学选择性催化侧链烷基化生成空间要求高的烷基苯

  摘要：

  DOI：

  10.1021/ja994432p

文献信息

• Contrasting chemoselectivities in the ultrasound and microwave assisted bromination reactions of substituted alkylaromatics with N-bromosuccinimide
  作者：Georgios A. Heropoulos、Giancarlo Cravotto、Constantinos G. Screttas、Barry R. Steele

  DOI：10.1016/j.tetlet.2007.03.023

  日期：2007.4

  and microwave assisted bromination reactions of various alkylaryls with N-bromosuccinimide, either neat or in water, shows diverse chemoselectivity. Thus, ring substitution occurs in water with ultrasound, whereas with microwaves both side-chain α-bromination and ring substitution occur. With neat reactants, side-chain α-bromination predominates for microwave assisted reactions. In the presence of water

  各种烷基芳基与N-溴丁二酰亚胺在纯净或水中的超声和微波辅助溴化反应显示出不同的化学选择性。因此，在超声波作用下，水中发生环取代，而在微波作用下，侧链α-溴化和环取代都发生。对于纯净的反应物，微波辅助反应中侧链α-溴化反应占主导地位。在水的存在下，微波促进的溴化的化学选择性类似于使用传统方法观察到的化学选择性。
• High intensity ultrasound-assisted reduction of sterically demanding nitroaromatics
  作者：Georgios A. Heropoulos、Spyros Georgakopoulos、Barry R. Steele

  DOI：10.1016/j.tetlet.2005.02.038

  日期：2005.4

  Sterically demanding nitroaromatic compounds have been prepared and reduced to their corresponding amines with high intensity ultrasound using hydrazine in the presence of a Raney nickel catalyst. These reactions were dependent on catalyst quality, solvent and ultrasonic amplitude and, in comparison to their silent reactions, proceeded much faster and afforded higher yields. (c) 2005 Elsevier Ltd. All rights reserved.