t-2-iodo-1-methylcyclohexan-r-1-yl acetate | 54605-31-1

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: t-2-iodo-1-methylcyclohexan-r-1-yl acetate
• 英文别名: trans-1-acetoxy-1-methyl-2-iodocyclohexane；r-2-Iod-c-1-methylcyclohexylacetat；[(1S,2S)-2-iodo-1-methylcyclohexyl] acetate
• CAS: 54605-31-1
• 化学式: C₉H₁₅IO₂
• 分子量: 282.121
• InChiKey: RPYQZCDRDPPKPW-IUCAKERBSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.8
• 重原子数：
  12
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.89
• 拓扑面积：
  26.3
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  碘苯二乙酸 、 环庚烷 在 碘 、 叔丁醇 作用下， 反应 14.0h， 以47%的产率得到t-2-iodo-1-methylcyclohexan-r-1-yl acetate
  参考文献：
  名称：

  Activation of Alkanes upon Reaction with PhI(OAc)2-I2

  摘要：

  DOI：

  10.1002/1521-3773(20020715)41:14<2556::aid-anie2556>3.0.co;2-c

文献信息

• Reactions of thallium(I) carboxylates and iodine with alkenes
  作者：Richard C. Cambie、Rodney C. Hayward、John L. Roberts、Peter S. Rutledge

  DOI：10.1039/p19740001858

  日期：——

  Treatment of an alkene with a thallium(I) carboxylate and iodine gives the corresponding vic-iodocarboxylate in high yield. The reactions are regiospecific and in conjunction with solvolysis of the products, offer an alternative to the Prévost reaction. Differences in the behaviour of thallium(I) carboxylates and silver carboxylates towards alkenes in the presence of iodine are discussed.

  用铊（烯烃的治疗我）羧酸酯和碘给出了相应的VIC以高收率-iodocarboxylate。该反应是区域特异性的，并与产物的溶剂分解结合，提供了Prévost反应的替代方法。讨论了在碘存在下of （I）羧酸盐和羧酸银对烯烃的行为差异。
• Cambie, Richard C.; Hume, Bruce A.; Rutledge, Peter S., Journal of the Chemical Society. Perkin transactions I, 1982, p. 413 - 419
  作者：Cambie, Richard C.、Hume, Bruce A.、Rutledge, Peter S.、Woodgate, Paul D.

  DOI：——

  日期：——
• Regioselective 1,2-Alkoxy, Hydroxy, and Acetoxy Iodination of Alkenes with I2 Catalyzed by Ce(SO3CF3)4
  作者：Nasser Iranpoor、Marzieh Shekarriz

  DOI：10.1016/s0040-4020(00)00358-6

  日期：2000.7

  The reaction of alkenes and iodine in water, alcohols and acetic acid is catalyzed with eerie triflate under mild conditions. The corresponding 1,2-alkoxy, acetoxy, and hydroxy iodides are obtained in good yields with easy procedure. (C) 2000 Elsevier Science Ltd. All rights reserved.
• De Mattos, Marcio C.S.; Sanseverino, Antonio Manzolillo, Journal of Chemical Research, 2004, # 9, p. 638 - 639
  作者：De Mattos, Marcio C.S.、Sanseverino, Antonio Manzolillo

  DOI：——

  日期：——